Rose-Marie Sjoberg
Overview
Explore the profile of Rose-Marie Sjoberg including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
349
Followers
0
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Recent Articles
1.
Fransson S, Martinez-Monleon A, Johansson M, Sjoberg R, Bjorklund C, Ljungman G, et al.
Sci Rep
. 2021 Jan;
10(1):22432.
PMID: 33384420
Neuroblastoma is the most common and deadly childhood tumor. Relapsed or refractory neuroblastoma has a very poor prognosis despite recent treatment advances. To investigate genomic alterations associated with relapse and...
2.
Siaw J, Javanmardi N, Van den Eynden J, Lind D, Fransson S, Martinez-Monleon A, et al.
Cell Rep
. 2020 Sep;
32(12):108171.
PMID: 32966799
High-risk neuroblastomas typically display an undifferentiated or poorly differentiated morphology. It is therefore vital to understand molecular mechanisms that block the differentiation process. We identify an important role for oncogenic...
3.
Javanmardi N, Fransson S, Djos A, Sjoberg R, Nilsson S, Truve K, et al.
Sci Rep
. 2019 Feb;
9(1):2199.
PMID: 30778092
The ALK tyrosine kinase receptor is oncogenically activated in neuroblastoma. Whereas numerous ALK fusion genes have been reported in different malignancies, in neuroblastoma ALK is mainly activated through point mutations....
4.
Kryh H, Caren H, Erichsen J, Sjoberg R, Abrahamsson J, Kogner P, et al.
BMC Genomics
. 2011 Sep;
12:443.
PMID: 21899760
Background: Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as...
5.
Kryh H, Abrahamsson J, Jegeras E, Sjoberg R, Devenney I, Kogner P, et al.
Int J Oncol
. 2011 Jul;
39(5):1063-71.
PMID: 21750863
The MYCN gene is frequently amplified in unfavorable neuroblastoma tumors. Therefore, this study aimed at characterizing the novel junctions connecting the amplified DNA segments (amplicons) and obtaining tumor-specific PCR fragments...
6.
Caren H, Djos A, Nethander M, Sjoberg R, Kogner P, Enstrom C, et al.
BMC Cancer
. 2011 Feb;
11:66.
PMID: 21314941
Background: Epigenetic mechanisms such as DNA methylation and histone modifications are important regulators of gene expression and are frequently involved in silencing tumor suppressor genes. Methods: In order to identify...
7.
Caren H, Kryh H, Nethander M, Sjoberg R, Trager C, Nilsson S, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(9):4323-8.
PMID: 20145112
Analysis of chromosomal aberrations is used to determine the prognosis of neuroblastomas (NBs) and to aid treatment decisions. MYCN amplification (MNA) alone is an incomplete poor prognostic factor, and chromosome...
8.
Wilzen A, Nilsson S, Sjoberg R, Kogner P, Martinsson T, Abel F
Int J Oncol
. 2009 Feb;
34(3):697-705.
PMID: 19212675
Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common solid tumor in childhood. By microarray expression analysis (Affymetrix HU133A) important players in the noradrenalin biosynthesis pathway...
9.
Caren H, Erichsen J, Olsson L, Enerback C, Sjoberg R, Abrahamsson J, et al.
BMC Genomics
. 2008 Jul;
9:353.
PMID: 18664255
Background: Neuroblastoma is a very heterogeneous pediatric tumor of the sympathetic nervous system showing clinically significant patterns of genetic alterations. Favorable tumors usually have near-triploid karyotypes with few structural rearrangements....
10.
Krona C, Caren H, Sjoberg R, Sandstedt B, Laureys G, Kogner P, et al.
Int J Oncol
. 2008 Feb;
32(3):575-83.
PMID: 18292934
Neuroblastomas are biologically and clinically heterogeneous tumours that most often occur sporadically in children at median age of 2 years. The PHOX2B gene is implicated in the development of the...