Tommer Schwarz
Overview
Explore the profile of Tommer Schwarz including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
124
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Recent Articles
1.
Yamaguchi T, Houlahan K, Zhu H, Kurganovs N, Livingstone J, Fox N, et al.
Cancer Discov
. 2025 Feb;
PMID: 39945744
Newly diagnosed prostate cancers differ dramatically in mutational composition and lethality. The most accurate clinical predictor of lethality is tumor tissue architecture, quantified as tumor grade. To interrogate the evolutionary...
2.
Johnson R, Stephens A, Mester R, Knyazev S, Kohn L, Freund M, et al.
Sci Transl Med
. 2024 May;
16(745):eade4510.
PMID: 38691621
Human inborn errors of immunity include rare disorders entailing functional and quantitative antibody deficiencies due to impaired B cells called the common variable immunodeficiency (CVID) phenotype. Patients with CVID face...
3.
Boltz T, Schwarz T, Bot M, Hou K, Caggiano C, Lapinska S, et al.
Am J Hum Genet
. 2024 Feb;
111(2):323-337.
PMID: 38306997
Genome-wide association studies (GWASs) have uncovered susceptibility loci associated with psychiatric disorders such as bipolar disorder (BP) and schizophrenia (SCZ). However, most of these loci are in non-coding regions of...
4.
Boltz T, Schwarz T, Bot M, Hou K, Caggiano C, Lapinska S, et al.
bioRxiv
. 2023 Jun;
PMID: 37293101
Genome-wide association studies (GWAS) have uncovered susceptibility loci associated with psychiatric disorders like bipolar disorder (BP) and schizophrenia (SCZ). However, most of these loci are in non-coding regions of the...
5.
Morova T, Ding Y, Huang C, Sar F, Schwarz T, Giambartolomei C, et al.
Nucleic Acids Res
. 2022 Dec;
51(3):e18.
PMID: 36546757
The vast majority of disease-associated single nucleotide polymorphisms (SNP) identified from genome-wide association studies (GWAS) are localized in non-coding regions. A significant fraction of these variants impact transcription factors binding...
6.
Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, et al.
Genome Med
. 2022 Nov;
14(1):128.
PMID: 36384576
No abstract available.
7.
Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, et al.
Genome Med
. 2022 Sep;
14(1):104.
PMID: 36085083
Background: Large medical centers in urban areas, like Los Angeles, care for a diverse patient population and offer the potential to study the interplay between genetic ancestry and social determinants...
8.
Baca S, Singler C, Zacharia S, Seo J, Morova T, Hach F, et al.
Nat Genet
. 2022 Sep;
54(9):1364-1375.
PMID: 36071171
Many genetic variants affect disease risk by altering context-dependent gene regulation. Such variants are difficult to study mechanistically using current methods that link genetic variation to steady-state gene expression levels,...
9.
Schwarz T, Boltz T, Hou K, Bot M, Duan C, Olde Loohuis L, et al.
HGG Adv
. 2022 May;
3(3):100103.
PMID: 35519825
Mapping genetic variants that regulate gene expression (eQTL mapping) in large-scale RNA sequencing (RNA-seq) studies is often employed to understand functional consequences of regulatory variants. However, the high cost of...
10.
Giambartolomei C, Seo J, Schwarz T, Freund M, Johnson R, Spisak S, et al.
Am J Hum Genet
. 2021 Nov;
108(12):2284-2300.
PMID: 34822763
Genome-wide association studies (GWASs) have identified more than 200 prostate cancer (PrCa) risk regions, which provide potential insights into causal mechanisms. Multiple lines of evidence show that a significant proportion...