Tobias Wauer
Overview
Explore the profile of Tobias Wauer including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
1662
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0
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Recent Articles
1.
Patil A, Strom A, Paulo J, Collings C, Ruff K, Shinn M, et al.
Cell
. 2023 Oct;
186(22):4936-4955.e26.
PMID: 37788668
Intrinsically disordered regions (IDRs) represent a large percentage of overall nuclear protein content. The prevailing dogma is that IDRs engage in non-specific interactions because they are poorly constrained by evolutionary...
2.
Wauer T, Simicek M, Schubert A, Komander D
Nature
. 2015 Sep;
526(7575):728.
PMID: 26416742
No abstract available.
3.
Wauer T, Simicek M, Schubert A, Komander D
Nature
. 2015 Jul;
524(7565):370-4.
PMID: 26161729
The E3 ubiquitin ligase PARKIN (encoded by PARK2) and the protein kinase PINK1 (encoded by PARK6) are mutated in autosomal-recessive juvenile Parkinsonism (AR-JP) and work together in the disposal of...
4.
Wauer T, Swatek K, Wagstaff J, Gladkova C, Pruneda J, Michel M, et al.
EMBO J
. 2014 Dec;
34(3):307-25.
PMID: 25527291
The protein kinase PINK1 was recently shown to phosphorylate ubiquitin (Ub) on Ser65, and phosphoUb activates the E3 ligase Parkin allosterically. Here, we show that PINK1 can phosphorylate every Ub...
5.
Wauer T, Komander D
Nat Struct Mol Biol
. 2014 Apr;
21(4):346-8.
PMID: 24699083
No abstract available.
6.
Birsa N, Norkett R, Wauer T, Mevissen T, Wu H, Foltynie T, et al.
J Biol Chem
. 2014 Mar;
289(21):14569-82.
PMID: 24671417
Mitochondrial transport plays an important role in matching mitochondrial distribution to localized energy production and calcium buffering requirements. Here, we demonstrate that Miro1, an outer mitochondrial membrane (OMM) protein crucial...
7.
Wauer T, Gerlach H, Mantri S, Hill J, Bayley H, Tanuj Sapra K
ACS Nano
. 2013 Dec;
8(1):771-9.
PMID: 24341760
Previously, we reported the manual assembly of lipid-coated aqueous droplets in oil to form two-dimensional (2D) networks in which the droplets are connected through single lipid bilayers. Here we assemble...
8.
Mevissen T, Hospenthal M, Geurink P, Elliott P, Akutsu M, Arnaudo N, et al.
Cell
. 2013 Jul;
154(1):169-84.
PMID: 23827681
Sixteen ovarian tumor (OTU) family deubiquitinases (DUBs) exist in humans, and most members regulate cell-signaling cascades. Several OTU DUBs were reported to be ubiquitin (Ub) chain linkage specific, but comprehensive...
9.
Keusekotten K, Elliott P, Glockner L, Fiil B, Damgaard R, Kulathu Y, et al.
Cell
. 2013 Jun;
153(6):1312-26.
PMID: 23746843
The linear ubiquitin (Ub) chain assembly complex (LUBAC) is an E3 ligase that specifically assembles Met1-linked (also known as linear) Ub chains that regulate nuclear factor κB (NF-κB) signaling. Deubiquitinases...
10.
Wauer T, Komander D
EMBO J
. 2013 Jun;
32(15):2099-112.
PMID: 23727886
Mutations in the protein Parkin are associated with Parkinson's disease (PD), the second most common neurodegenerative disease in men. Parkin is an E3 ubiquitin (Ub) ligase of the structurally uncharacterized...