Tycho E T Mevissen
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Explore the profile of Tycho E T Mevissen including associated specialties, affiliations and a list of published articles.
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19
Citations
1677
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Recent Articles
1.
Mevissen T, Kummecke M, Schmid E, Farnung L, Walter J
Cell
. 2024 Nov;
187(25):7091-7106.e24.
PMID: 39547228
In transcription-coupled nucleotide excision repair (TC-NER), stalled RNA polymerase II (RNA Pol II) binds CSB and CRL4, which cooperate with UVSSA and ELOF1 to recruit TFIIH. To explore the mechanism...
2.
Mevissen T, Kummecke M, Schmid E, Farnung L, Walter J
bioRxiv
. 2024 Aug;
PMID: 39091863
In transcription-coupled repair, stalled RNA polymerase II (Pol II) is recognized by CSB and CRL4, which co-operate with UVSSSA and ELOF1 to recruit TFIIH for nucleotide excision repair (TC-NER). To...
3.
Mevissen T, Prasad A, Walter J
Cell Rep
. 2023 Feb;
42(2):112125.
PMID: 36807144
Tripartite motif-containing protein 21 (TRIM21) is a cytosolic antibody receptor and E3 ubiquitin ligase that promotes destruction of a broad range of pathogens. TRIM21 also underlies the antibody-dependent protein targeting...
4.
van der Weegen Y, de Lint K, van den Heuvel D, Nakazawa Y, Mevissen T, van Schie J, et al.
Nat Cell Biol
. 2021 Jun;
23(6):595-607.
PMID: 34108663
Cells employ transcription-coupled repair (TCR) to eliminate transcription-blocking DNA lesions. DNA damage-induced binding of the TCR-specific repair factor CSB to RNA polymerase II (RNAPII) triggers RNAPII ubiquitylation of a single...
5.
van der Weegen Y, Golan-Berman H, Mevissen T, Apelt K, Gonzalez-Prieto R, Goedhart J, et al.
Nat Commun
. 2020 Nov;
11(1):5734.
PMID: 33159085
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Spagnol V, Oliveira C, Randle S, Passos P, Correia C, Simaroli N, et al.
Biochim Biophys Acta Gen Subj
. 2020 Oct;
1865(1):129754.
PMID: 33010352
Background: Ubiquitously eXpressed Transcript isoform 2 (UXTV2) is a prefoldin-like protein involved in NF-κB signaling, apoptosis, and the androgen and estrogen response. UXT-V2 is a cofactor in the NF-κB transcriptional...
7.
van der Weegen Y, Golan-Berman H, Mevissen T, Apelt K, Gonzalez-Prieto R, Goedhart J, et al.
Nat Commun
. 2020 May;
11(1):2104.
PMID: 32355176
The response to DNA damage-stalled RNA polymerase II (RNAPIIo) involves the assembly of the transcription-coupled repair (TCR) complex on actively transcribed strands. The function of the TCR proteins CSB, CSA...
8.
Swatek K, Usher J, Kueck A, Gladkova C, Mevissen T, Pruneda J, et al.
Nature
. 2019 Aug;
572(7770):533-537.
PMID: 31413367
Protein ubiquitination is a multi-functional post-translational modification that affects all cellular processes. Its versatility arises from architecturally complex polyubiquitin chains, in which individual ubiquitin moieties may be ubiquitinated on one...
9.
Mevissen T, Komander D
Annu Rev Biochem
. 2017 May;
86:159-192.
PMID: 28498721
Protein ubiquitination is one of the most powerful posttranslational modifications of proteins, as it regulates a plethora of cellular processes in distinct manners. Simple monoubiquitination events coexist with more complex...
10.
Mevissen T, Kulathu Y, Mulder M, Geurink P, Maslen S, Gersch M, et al.
Nature
. 2016 Oct;
538(7625):402-405.
PMID: 27732584
The post-translational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology. Eight distinct chain linkage types co-exist in polyubiquitin and are independently regulated in cells. This 'ubiquitin...