Daniel Krappmann
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Explore the profile of Daniel Krappmann including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Rosenlehner T, Pennavaria S, Akcabozan B, Jahani S, ONeill T, Krappmann D, et al.
Sci Signal
. 2024 Oct;
17(859):eadi8753.
PMID: 39436996
Ribosomal biosynthesis in nucleoli is an energy-demanding process driven by all RNA polymerases and hundreds of auxiliary proteins. We investigated how this process is regulated in activated T lymphocytes by...
2.
Dabbah-Krancher G, Ruchinskas A, Kallarakal M, Lee K, Bauman B, Epstein B, et al.
Eur J Immunol
. 2024 Oct;
54(12):e2451245.
PMID: 39359035
A20 is a dual-function ubiquitin-editing enzyme that maintains immune homeostasis by restraining inflammation. Although A20 serves a similar negative feedback function for T-cell receptor (TCR) signaling, the molecular mechanisms utilized...
3.
Krappmann D, Hirsch A
Chemistry
. 2024 Jul;
30(55):e202401391.
PMID: 38984830
We report the synthesis and characterization of library of new 2,3-disubstituted norbornadiene/quadricyclane couples. For the first time, the para-tolylsulfone moiety was employed as electron-withdrawing substituent in combination with a variety...
4.
Heine S, Alessandrini F, Grosch J, Grass C, Heldner A, Schnautz B, et al.
Front Immunol
. 2024 Jun;
15:1397072.
PMID: 38915403
Background: Allergen-specific immunotherapy (AIT) is able to restore immune tolerance to allergens in allergic patients. However, some patients do not or only poorly respond to current treatment protocols. Therefore, there...
5.
Moud B, Ober F, ONeill T, Krappmann D
Front Immunol
. 2024 Jun;
15:1412347.
PMID: 38863711
CARD-BCL10-MALT1 (CBM) signalosomes connect distal signaling of innate and adaptive immune receptors to proximal signaling pathways and immune activation. Four CARD scaffold proteins (CARD9, 10, 11, 14) can form seeds...
6.
Tofaute M, Weller B, Grass C, Halder H, Dohai B, Falter-Braun P, et al.
Biosci Rep
. 2023 Dec;
44(1).
PMID: 38131452
Upon SARS-CoV-2 infection, patients with severe forms of COVID-19 often suffer from a dysregulated immune response and hyperinflammation. Aberrant expression of cytokines and chemokines is associated with strong activation of...
7.
Schmidt H, Raj T, ONeill T, Muschaweckh A, Giesert F, Negraschus A, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(48):e2309205120.
PMID: 37988467
Constitutive activation of the MALT1 paracaspase in conventional T cells of (TRAF6 Binding Mutant = TBM) mice causes fatal inflammation and autoimmunity, but the involved targets and underlying molecular mechanisms...
8.
Wimberger N, Ober F, Avar G, Grau M, Xu W, Lenz G, et al.
Blood
. 2023 Aug;
142(23):1985-2001.
PMID: 37623434
Constitutive mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) activity drives survival of malignant lymphomas addicted to chronic B-cell receptor signaling, oncogenic CARD11, or the API2-MALT1 (also BIRC3::MALT1) fusion oncoprotein....
9.
Hemauer F, Krappmann D, Schwaab V, Hussain Z, Marie Freiberger E, Waleska-Wellnhofer N, et al.
J Chem Phys
. 2023 Aug;
159(7).
PMID: 37602805
The transition to renewable energy sources comes along with the search for new energy storage solutions. Molecular solar thermal systems directly harvest and store solar energy in a chemical manner....
10.
Di Pilato M, Gao Y, Sun Y, Fu A, Grass C, Seeholzer T, et al.
J Immunother Precis Oncol
. 2023 May;
6(2):61-73.
PMID: 37214210
Introduction: Regulatory T cells (Tregs) play a critical role in the maintenance of immune homeostasis but also protect tumors from immune-mediated growth control or rejection and pose a significant barrier...