Theo J C Van Berkel
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Explore the profile of Theo J C Van Berkel including associated specialties, affiliations and a list of published articles.
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167
Citations
4759
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Recent Articles
1.
Medina I, Wieland E, Temmerman L, Otten J, Bermudez B, Bot I, et al.
Eur J Immunol
. 2024 Sep;
54(11):e2350943.
PMID: 39233527
Macrophage infiltration and accumulation in the atherosclerotic lesion are associated with plaque progression and instability. Depletion of macrophages from the lesion might provide valuable insights into plaque stabilization processes. Therefore,...
2.
Singh A, Kraaijeveld A, Curaj A, Wichapong K, Hammerich L, de Jager S, et al.
Front Immunol
. 2024 May;
15:1327051.
PMID: 38807599
Introduction: The CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in chronic inflammation in humans. Recent observations of elevated CCL18 plasma levels in patients with acute cardiovascular syndromes...
3.
Hoekstra M, Van Eck M, Van Berkel T
Arterioscler Thromb Vasc Biol
. 2023 May;
43(6):832-835.
PMID: 37128922
Hyperlipidemia is a major risk factor for the development of atherosclerotic cardiovascular disease. Lipid-lowering drug therapies therefore still form the heart of the ongoing battle against the occurrence of cardiovascular...
4.
Segers F, Ruder A, Westra M, Lammers T, Dadfar S, Roemhild K, et al.
Cardiovasc Res
. 2022 Mar;
118(17):3346-3359.
PMID: 35325057
Aims: (Ultra) Small superparamagnetic iron oxide nanoparticles, (U)SPIO, are widely used as magnetic resonance imaging contrast media and assumed to be safe for clinical applications in cardiovascular disease. As safety...
5.
Biessen E, Van Berkel T
Arterioscler Thromb Vasc Biol
. 2021 Oct;
41(12):2855-2865.
PMID: 34645280
While the promise of oligonucleotide therapeutics, such as (chemically modified) ASO (antisense oligonucleotides) and short interfering RNAs, is undisputed from their introduction onwards, their unfavorable pharmacokinetics and intrinsic capacity to...
6.
Ouweneel A, Zhao Y, Calpe-Berdiel L, Lammers B, Hoekstra M, Van Berkel T, et al.
Atherosclerosis
. 2021 Jan;
319:79-85.
PMID: 33494008
Background And Aims: There is extensive evidence from bone marrow transplantation studies that hematopoietic ATP binding cassette A1 (Abca1) is atheroprotective in low-density lipoprotein receptor (Ldlr) deficient mice. In contrast,...
7.
Hoekstra M, van der Sluis R, Hildebrand R, Lammers B, Zhao Y, Pratico D, et al.
Arterioscler Thromb Vasc Biol
. 2020 Jan;
40(3):611-623.
PMID: 31941380
Objective: We tested the hypothesis that enlarged, dysfunctional HDL (high-density lipoprotein) particles contribute to the augmented atherosclerosis susceptibility associated with SR-BI (scavenger receptor BI) deficiency in mice. Approach and Results:...
8.
Fontaine M, Westra M, Bot I, Jin H, Franssen A, Bot M, et al.
Sci Rep
. 2019 Oct;
9(1):14547.
PMID: 31601924
The anti-apoptotic protein myeloid cell leukemia 1 (Mcl-1) plays an important role in survival and differentiation of leukocytes, more specifically of neutrophils. Here, we investigated the impact of myeloid Mcl-1...
9.
Korporaal S, Molenaar T, Lutters B, Meurs I, Drost-Verhoef S, Kuiper J, et al.
J Clin Med
. 2019 Aug;
8(8).
PMID: 31434351
Background: Membrane-exposed sulfatides are proposed to contribute to P-selectin-dependent platelet aggregation. Here, we demonstrated that P-selectin-mediated platelet aggregation on a collagen-coated surface under flow indeed depended on sulfatides and that...
10.
Willoughby J, Chan A, Sehgal A, Butler J, Nair J, Racie T, et al.
Mol Ther
. 2017 Oct;
26(1):105-114.
PMID: 28988716
The hepatocyte-specific asialoglycoprotein receptor (ASGPR) is an ideal candidate for targeted drug delivery to the liver due to its high capacity for substrate clearance from circulation together with its well-conserved...