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Erik A L Biessen

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Articles 174
Citations 3947
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Recent Articles
1.
Vermeulen I, Li M, van Mourik H, Yadati T, Eijkel G, Balluff B, et al.
FEBS J . 2024 Dec; PMID: 39726152
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) progressing to metabolic dysfunction-associated steatohepatitis (MASH), characterized by hepatic inflammation, has significantly increased in recent years due to unhealthy dietary practices...
2.
Medina I, Wieland E, Temmerman L, Otten J, Bermudez B, Bot I, et al.
Eur J Immunol . 2024 Sep; 54(11):e2350943. PMID: 39233527
Macrophage infiltration and accumulation in the atherosclerotic lesion are associated with plaque progression and instability. Depletion of macrophages from the lesion might provide valuable insights into plaque stabilization processes. Therefore,...
3.
Adam S, Maas S, Huchzermeier R, Rakateli L, Abschlag K, Hohl M, et al.
EBioMedicine . 2024 Aug; 107:105293. PMID: 39146692
Background: Female mice are more resistant to obesogenic effects of a high-fat diet (HFD), compared to male mice. Although the underlying mechanisms are poorly understood, sex hormones seem to play...
4.
Jin H, Zhang C, Nagenborg J, Juhasz P, Ruder A, Sikkink C, et al.
Cardiovasc Diabetol . 2024 Jul; 23(1):240. PMID: 38978031
Background: Metabolism is increasingly recognized as a key regulator of the function and phenotype of the primary cellular constituents of the atherosclerotic vascular wall, including endothelial cells, smooth muscle cells,...
5.
Singh A, Kraaijeveld A, Curaj A, Wichapong K, Hammerich L, de Jager S, et al.
Front Immunol . 2024 May; 15:1327051. PMID: 38807599
Introduction: The CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in chronic inflammation in humans. Recent observations of elevated CCL18 plasma levels in patients with acute cardiovascular syndromes...
6.
Rademakers T, Manca M, Jin H, Orban T, Perisic L, Frissen H, et al.
Angiogenesis . 2024 May; 27(3):461-474. PMID: 38780883
The presence of atherosclerotic plaque vessels is a critical factor in plaque destabilization. This may be attributable to the leaky phenotype of these microvessels, although direct proof for this notion...
7.
Lu C, Donners M, de Baaij J, Jin H, Otten J, Manca M, et al.
Front Immunol . 2024 Feb; 15:1286382. PMID: 38410507
Introduction: The impact of cardiovascular disease (CVD) risk factors, encompassing various biological determinants and unhealthy lifestyles, on the functional dynamics of circulating monocytes-a pivotal cell type in CVD pathophysiology remains...
8.
Christ A, Maas S, Jin H, Lu C, Legein B, Wijnands E, et al.
Free Radic Biol Med . 2023 Dec; 210:406-415. PMID: 38061606
Background And Aims: Dendritic cells (DCs), professional antigen-presenting cells, play an important role in pathologies by controlling adaptive immune responses. However, their adaptation to and functionality in hypercholesterolemia, a driving...
9.
Nagenborg J, Jin H, Ruder A, Temmerman L, Mees B, Schalkwijk C, et al.
Front Immunol . 2023 Nov; 14:1165306. PMID: 37920458
Introduction: Inhibition of STAT5 was recently reported to reduce murine atherosclerosis. However, the role of STAT5 isoforms, and more in particular STAT5A in macrophages in the context of human atherosclerosis...
10.
Wieland E, Kempen L, Lu C, Donners M, Biessen E, Goossens P
STAR Protoc . 2023 Sep; 4(4):102601. PMID: 37742177
Recent technical advances, such as single-cell RNA sequencing and mass cytometry, improve identification of cell types and subsets in a range of healthy and diseased tissues at the expense of...