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Tetsuo Takagi

Explore the profile of Tetsuo Takagi including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 252
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Recent Articles
1.
Nishimura S, Inai M, Takagi T, Nonaka Y, Urashima S, Honda K, et al.
J Oleo Sci . 2017 Jul; 66(8):917-924. PMID: 28701655
Previous studies have shown that medium-chain triacylglycerols (MCTs) exert favorable effects on protein metabolism. This study evaluated the effects of the dietary intake of MCTs on rat skeletal muscle mass...
2.
Nonaka Y, Takagi T, Inai M, Nishimura S, Urashima S, Honda K, et al.
J Oleo Sci . 2016 Jul; 65(8):693-9. PMID: 27430387
Coconut oil has recently attracted considerable attention as a potential Alzheimer's disease therapy because it contains large amounts of medium-chain fatty acids (MCFAs) and its consumption is thought to stimulate...
3.
Tokmakov A, Kurotani A, Takagi T, Toyama M, Shirouzu M, Fukami Y, et al.
J Biol Chem . 2012 Jun; 287(32):27106-16. PMID: 22674579
Post-translational modifications (PTMs) are required for proper folding of many proteins. The low capacity for PTMs hinders the production of heterologous proteins in the widely used prokaryotic systems of protein...
4.
Handa N, Takagi T, Saijo S, Kishishita S, Takaya D, Toyama M, et al.
Acta Crystallogr D Biol Crystallogr . 2011 May; 67(Pt 5):480-7. PMID: 21543851
AMP-activated protein kinase (AMPK) is a serine/threonine kinase that functions as a sensor to maintain energy balance at both the cellular and the whole-body levels and is therefore a potential...
5.
Kukimoto-Niino M, Yoshikawa S, Takagi T, Ohsawa N, Tomabechi Y, Terada T, et al.
J Biol Chem . 2011 Apr; 286(25):22570-9. PMID: 21504895
Ca(2+)/calmodulin (CaM)-dependent protein kinase (CaMK) kinase (CaMKK) is a member of the CaMK cascade that mediates the response to intracellular Ca(2+) elevation. CaMKK phosphorylates and activates CaMKI and CaMKIV, which...
6.
Shida M, Arakawa A, Ishii R, Kishishita S, Takagi T, Kukimoto-Niino M, et al.
Acta Crystallogr D Biol Crystallogr . 2010 Feb; 66(Pt 3):223-32. PMID: 20179333
The 70 kDa heat-shock proteins (Hsp70s) are highly conserved chaperones that are involved in several cellular processes, such as protein folding, disaggregation and translocation. In this study, the crystal structures...
7.
Kurotani A, Takagi T, Toyama M, Shirouzu M, Yokoyama S, Fukami Y, et al.
FASEB J . 2009 Nov; 24(4):1095-104. PMID: 19940260
High-throughput cell-free protein synthesis is being used increasingly in structural/functional genomics projects. However, the factors determining expression success are poorly understood. Here, we evaluated the expression of 3066 human proteins...
8.
Tani T, Ayuzawa R, Takagi T, Kanehira T, Maurya D, Tamura M
Mol Cell Biochem . 2008 Jun; 315(1-2):185-93. PMID: 18543083
We previously demonstrated that angiotensin II (Ang II) receptor signaling is involved in azoxymethane-induced mouse colon tumorigenesis. In order to clarify the role of Ang II in COX-2 expression in...
9.
Kukimoto-Niino M, Takagi T, Akasaka R, Murayama K, Uchikubo-Kamo T, Terada T, et al.
J Biol Chem . 2006 Aug; 281(42):31843-53. PMID: 16928684
Rap2-interacting protein x (RPIPx) is a homolog of RPIP8, a specific effector of Rap2 GTPase. The N-terminal region of RPIP8, which contains the RUN domain, interacts with Rap2. Using cell-free...
10.
Kanehira T, Tani T, Takagi T, Nakano Y, Howard E, Tamura M
Cancer Res . 2005 Sep; 65(17):7660-5. PMID: 16140932
To clarify an involvement of angiotensin II signaling in lung neoplasia, we have examined the effect of angiotensin II receptor deficiency on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis. Male angiotensin II type...