Teddy T C Yang
Overview
Explore the profile of Teddy T C Yang including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
330
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Recent Articles
1.
Suk H, Zhou C, Yang T, Zhu H, Yu R, Olabisi O, et al.
J Biol Chem
. 2012 Dec;
288(5):3477-88.
PMID: 23258544
Insulin resistance, hyperlipidemia, and cardiovascular complications are common dysregulations of metabolic syndrome. Transplant patients treated with immunosuppressant drugs such as cyclosporine A (CsA), an inhibitor of calcineurin phosphatase, frequently develop...
2.
Yang T, Chow C
Methods Mol Biol
. 2011 Nov;
809:75-84.
PMID: 22113269
Transcription factors recruit a wide variety of associated co-factors to regulate gene expression. These co-factors include protein kinases, phosphatases, deacetylases, methylases, and ubiquitin ligases, etc. To identify novel protein kinases...
3.
Burington B, Yue P, Shi X, Advani R, Lau J, Tan J, et al.
Sci Transl Med
. 2011 Mar;
3(74):74ra22.
PMID: 21411738
The primary function of B cells, critical components of the adaptive immune response, is to produce antibodies against foreign antigens, as well as to perform isotype class switching, which changes...
4.
Zhu H, Suk H, Yu R, Brancho D, Olabisi O, Yang T, et al.
Mol Cell Biol
. 2010 Jul;
30(18):4379-90.
PMID: 20647544
Calcineurin is a widely expressed and highly conserved Ser/Thr phosphatase. Calcineurin is inhibited by the immunosuppressant drug cyclosporine A (CsA) or tacrolimus (FK506). The critical role of CsA/FK506 as an...
5.
Yang T, Yu R, Agadir A, Gao G, Campos-Gonzalez R, Tournier C, et al.
Mol Cell Biol
. 2008 Mar;
28(10):3489-501.
PMID: 18347059
The target of rapamycin (TOR) signaling regulates the nucleocytoplasmic shuttling of transcription factors in yeast. Whether the mammalian counterpart of TOR (mTOR) also regulates nucleocytoplasmic shuttling is not known. Using...
6.
Olabisi O, Soto-Nieves N, Nieves E, Yang T, Yang X, Yu R, et al.
Mol Cell Biol
. 2008 Feb;
28(9):2860-71.
PMID: 18299389
ADP-ribosylation is a reversible posttranslational modification mediated by poly-ADP-ribose polymerase (PARP). The results of recent studies demonstrate that ADP-ribosylation contributes to transcription regulation. Here, we report that transcription factor NFAT...
7.
Yang X, Yang T, Schubert W, Factor S, Chow C
Dev Biol
. 2007 Jan;
303(2):825-37.
PMID: 17198697
Thin spongy myocardium is critical at early embryonic stage [before embryonic day (E) 13.5 in mice] to allow diffusion of oxygen and nutrients to the developing cardiomyocytes. However, establishment of...
8.
Yang T, Suk H, Yang X, Olabisi O, Yu R, Durand J, et al.
Mol Cell Biol
. 2006 Aug;
26(20):7372-87.
PMID: 16908540
Compromised immunoregulation contributes to obesity and complications in metabolic pathogenesis. Here, we demonstrate that the nuclear factor of activated T cell (NFAT) group of transcription factors contributes to glucose and...
9.
Yang T, Ung P, Rincon M, Chow C
J Biol Chem
. 2006 Feb;
281(17):11541-52.
PMID: 16500900
Inflammatory cytokines such as interleukin-1 and tumor necrosis factor-alpha modulate a transcription factor cascade in the liver to induce and sustain an acute and systemic defense against foreign entities. The...
10.
Yang T, Xiong Q, Graef I, Crabtree G, Chow C
Mol Cell Biol
. 2005 Jan;
25(3):907-20.
PMID: 15657420
Integration of protein kinases into transcription activation complexes influences the magnitude of gene expression. The nuclear factor of activated T cells (NFAT) group of proteins are critical transcription factors that...