Philipp E Scherer
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Explore the profile of Philipp E Scherer including associated specialties, affiliations and a list of published articles.
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448
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31809
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Recent Articles
1.
Kim D, Funcke J, Chen S, Min K, Onodera T, Kim M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060507
Endotrophin (ETP), a cleavage product of the C5 domain of collagen VI α3 (COL6A3), plays a crucial role in extracellular matrix remodeling. Previously established knockout (KO) mouse models primarily reflect...
2.
Youm Y, Gliniak C, Zhang Y, Dlugos T, Scherer P, Dixit V
Nat Aging
. 2025 Feb;
PMID: 39972172
Age-related thymic involution precedes aging of all other organs in vertebrates and initiates the process of declining T cell diversity, which leads to eventual immune dysfunction. Whether FGF21, a liver-derived...
3.
Zhao S, Zhu Q, Lee W, Funcke J, Zhang Z, Wang M, et al.
Cell Rep
. 2025 Jan;
44(1):115165.
PMID: 39792554
Hepatic stellate cells (HSCs) are key drivers of local fibrosis. Adiponectin, conventionally thought of as an adipokine, is also expressed in quiescent HSCs. However, the impact of its local expression...
4.
Yu X, Chen S, Funcke J, Straub L, Pirro V, Emont M, et al.
Cell Metab
. 2024 Dec;
37(1):187-204.e7.
PMID: 39642881
Obesity is a chronic disease that contributes to the development of insulin resistance, type 2 diabetes (T2D), and cardiovascular risk. Glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) and glucagon-like peptide-1 (GLP-1)...
5.
Liu W, Mao R, Nga Le T, West G, Varadharajan V, Banerjee R, et al.
Gastroenterology
. 2024 Nov;
168(3):508-524.
PMID: 39522890
Background & Aims: In Crohn's disease, wrapping of mesenteric fat around the bowel wall, so-called "creeping fat," is highly associated with strictures. The strongest contributor to luminal narrowing in strictures...
6.
Li C, Sun X, Funcke J, Vanharanta L, Joffin N, Li Y, et al.
bioRxiv
. 2024 Aug;
PMID: 39211078
Adipogenin (Adig) is an evolutionarily conserved microprotein and is highly expressed in adipose tissues and testis. Here, we identify Adig as a critical regulator for lipid droplet formation in adipocytes....
7.
Kusminski C, Perez-Tilve D, Muller T, DiMarchi R, Tschop M, Scherer P
Cell
. 2024 Jul;
187(15):3829-3853.
PMID: 39059360
For more than a century, physicians have searched for ways to pharmacologically reduce excess body fat. The tide has finally turned with recent advances in biochemically engineered agonists for the...
8.
Flannery A, Bu D, Botkins M, Gianella F, Zhang N, An Z, et al.
Kidney360
. 2024 Jul;
5(8):1087-1093.
PMID: 39024016
No abstract available.
9.
Lee P, Jung I, Thussu S, Patel V, Wagoner R, Burks K, et al.
iScience
. 2024 Jul;
27(7):110104.
PMID: 38989470
Coronary artery disease (CAD) remains a leading cause of disease burden globally, and there is a persistent need for new therapeutic targets. Instrumental variable (IV) and genetic colocalization analyses can...
10.
Li Y, Onodera T, Scherer P
Trends Endocrinol Metab
. 2024 Jul;
35(7):674-675.
PMID: 38981443
No abstract available.