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Tatiana A Soboleva

Explore the profile of Tatiana A Soboleva including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 528
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Recent Articles
1.
Apu M, Shirokikh N, Khochbin S, Soboleva T
Curr Protoc . 2023 Nov; 3(11):e920. PMID: 37933593
Human fertility is declining in Western countries, and it is becoming increasingly clear that male infertility plays a pivotal role in the overall fertility decline. To understand the process that...
2.
Jiang X, Wen J, Paver E, Wu Y, Sun G, Bullman A, et al.
EMBO Rep . 2021 Aug; 22(8):e52462. PMID: 34350706
Testis-specific regulators of chromatin function are commonly ectopically expressed in human cancers, but their roles are poorly understood. Examination of 81 primary Hodgkin lymphoma (HL) samples showed that the ectopic...
3.
Jiang X, Soboleva T, Tremethick D
Cells . 2020 Apr; 9(4). PMID: 32252453
The dynamic packaging of DNA into chromatin regulates all aspects of genome function by altering the accessibility of DNA and by providing docking pads to proteins that copy, repair and...
4.
Anuar N, Kurscheid S, Field M, Zhang L, Rebar E, Gregory P, et al.
Genome Biol . 2019 Feb; 20(1):23. PMID: 30704500
Background: Altering the biochemical makeup of chromatin by the incorporation of histone variants during development represents a key mechanism in regulating gene expression. The histone variant H2A.B, H2A.B.3 in mice,...
5.
Soboleva T, Tremethick D
Methods Mol Biol . 2018 Aug; 1832:169-184. PMID: 30073527
Chromatin is a dynamic macromolecular structure comprised of histones and a wealth of non-histone proteins. Recently, it has become clear that RNA is also an integral component of chromatin playing...
6.
Moretti C, Serrentino M, Ialy-Radio C, Delessard M, Soboleva T, Tores F, et al.
Cell Death Differ . 2017 May; 24(6):1029-1044. PMID: 28475176
Sperm differentiation requires unique transcriptional regulation and chromatin remodeling after meiosis to ensure proper compaction and protection of the paternal genome. Abnormal sperm chromatin remodeling can induce sperm DNA damage,...
7.
Soboleva T, Parker B, Nekrasov M, Hart-Smith G, Tay Y, Tng W, et al.
PLoS Genet . 2017 Feb; 13(2):e1006633. PMID: 28234895
The replacement of histone H2A with its variant forms is critical for regulating all aspects of genome organisation and function. The histone variant H2A.B appeared late in evolution and is...
8.
Soboleva T, Nekrasov M, Ryan D, Tremethick D
Trends Genet . 2014 Apr; 30(5):199-209. PMID: 24768041
The function of a eukaryotic cell crucially depends on accurate gene transcription to ensure the right genes are expressed whereas unrequired genes are repressed. Therefore, arguably, one of the most...
9.
Nekrasov M, Soboleva T, Jack C, Tremethick D
Nucleus . 2013 Nov; 4(6):431-8. PMID: 24213378
Considerable attention has been given to the understanding of how nucleosomes are altered or removed from the transcription start site of RNA polymerase II genes to enable transcription to proceed....
10.
Nekrasov M, Amrichova J, Parker B, Soboleva T, Jack C, Williams R, et al.
Nat Struct Mol Biol . 2012 Oct; 19(11):1076-83. PMID: 23085713
Although it has been clearly established that well-positioned histone H2A.Z-containing nucleosomes flank the nucleosome-depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information...