Tamir Tuller
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Explore the profile of Tamir Tuller including associated specialties, affiliations and a list of published articles.
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Articles
158
Citations
3264
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Recent Articles
1.
Burghardt M, Tuller T
Synth Syst Biotechnol
. 2025 Jan;
10(2):337-345.
PMID: 39802156
Transient expression in Tobacco is a popular way to produce recombinant proteins in plants. The design of various expression vectors, delivered into the plant by , has enabled high production...
2.
Roopin M, Zafrir Z, Siridechadilok B, Suphatrakul A, Julander J, Tuller T
Nucleic Acids Res
. 2025 Jan;
53(2).
PMID: 39797731
Many viruses of the Flaviviridae family, including the Zika virus (ZIKV), are human pathogens of significant public health concerns. Despite extensive research, there are currently no approved vaccines available for...
3.
Sidi T, Bahiri-Elitzur S, Tuller T, Kolodny R
Proc Natl Acad Sci U S A
. 2024 Dec;
122(1):e2410003121.
PMID: 39739812
Selective pressure acts on the codon use, optimizing multiple, overlapping signals that are only partially understood. We trained AI models to predict codons given their amino acid sequence in the...
4.
Gutman T, Tuller T
PLoS Comput Biol
. 2024 Dec;
20(12):e1012685.
PMID: 39724131
The P-glycoprotein efflux pump, encoded by the MDR1 gene, is an ATP-driven transporter capable of expelling a diverse array of compounds from cells. Overexpression of this protein is implicated in...
5.
Cohen S, Bergman S, Lynn N, Tuller T
Genome Med
. 2024 Dec;
16(1):152.
PMID: 39716183
Background: CRISPR is widely used to silence genes by inducing mutations expected to nullify their expression. While numerous computational tools have been developed to design single-guide RNAs (sgRNAs) with high...
6.
Bergman S, Tuller T
NPJ Syst Biol Appl
. 2024 Sep;
10(1):100.
PMID: 39227603
CRISPR is a precise and effective genome editing technology; but despite several advancements during the last decade, our ability to computationally design gRNAs remains limited. Most predictive models have relatively...
7.
Reingewertz T, Ben-Maimon M, Zafrir Z, Tuller T, Horovitz A
Protein Sci
. 2024 Jul;
33(8):e5087.
PMID: 39074255
The Escherichia coli GroEL/ES chaperonin system facilitates protein folding in an ATP-driven manner. There are <100 obligate clients of this system in E. coli although GroEL can interact and assist...
8.
Bergman S, Tuller T
PLoS Comput Biol
. 2024 Jun;
20(6):e1012214.
PMID: 38848440
CRISPR is a gene editing technology which enables precise in-vivo genome editing; but its potential is hampered by its relatively low specificity and sensitivity. Improving CRISPR's on-target and off-target effects...
9.
Bader S, Tuller T
Comput Struct Biotechnol J
. 2024 May;
23:1740-1754.
PMID: 38689718
The modeling of miRNA-mRNA interactions holds significant implications for synthetic biology and human health. However, this research area presents specific challenges due to the multifaceted nature of mRNA downregulation by...
10.
Arbel-Groissman M, Menuhin-Gruman I, Yehezkeli H, Naki D, Bergman S, Udi Y, et al.
Methods Mol Biol
. 2024 Mar;
2760:371-392.
PMID: 38468099
Genetic engineering has revolutionized our ability to manipulate DNA and engineer organisms for various applications. However, this approach can lead to genomic instability, which can result in unwanted effects such...