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Npj Systems Biology and Applications

Npj Systems Biology and Applications is a scientific journal, published since 2015 in English. The journal's country of origin is United Kingdom and its primary focus area is biology.

Details
Abbr. NPJ Syst Biol Appl
Start 2015
End Continuing
e-ISSN 2056-7189
Country United Kingdom
Language English
Specialty Biology
Metrics
h-index / Ranks: 9569 35
SJR / Ranks: 2663 1248
CiteScore / Ranks: 3145 6.70
JIF / Ranks: 2264 4.0
Recent Articles
1.
Srivastava A, Vinod P
NPJ Syst Biol Appl . 2025 Mar; 11(1):26. PMID: 40082472
Cancer metabolism is characterized by significant heterogeneity, presenting challenges for treatment efficacy and patient outcomes. Understanding this heterogeneity and its regulatory mechanisms at single-cell resolution is crucial for developing personalized...
2.
Szabo G, Bonaiuti P, Ciliberto A, Horvath A
NPJ Syst Biol Appl . 2025 Mar; 11(1):25. PMID: 40082471
Accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing-based object tracking methods. In recent years, many applications have attempted to integrate...
3.
Guilberteau J, Jain P, Jolly M, Pouchol C, Pouradier Duteil N
NPJ Syst Biol Appl . 2025 Mar; 11(1):24. PMID: 40050291
Phenotypic heterogeneity along the epithelial-mesenchymal (E-M) axis contributes to cancer metastasis and drug resistance. Recent experimental efforts have collated detailed time-course data on the emergence and dynamics of E-M heterogeneity...
4.
Hu Q, Lu X, Xue Z, Wang R
NPJ Syst Biol Appl . 2025 Mar; 11(1):23. PMID: 40032872
With rapid advances in biological technology and computational approaches, inferring specific gene regulatory networks from data alone during cell fate decisions, including determining direct regulations and their intensities between biomolecules,...
5.
Vaisband M, von Bornhaupt V, Schmid N, Abulizi I, Hasenauer J
NPJ Syst Biol Appl . 2025 Mar; 11(1):22. PMID: 40025020
Stochastic differential equations (SDEs) are one of the most commonly studied probabilistic dynamical systems, and widely used to model complex biological processes. Building upon the previously introduced idea of performing...
6.
Mishra B, Gou Y, Tan Z, Wang Y, Hu G, Athar M, et al.
NPJ Syst Biol Appl . 2025 Feb; 11(1):21. PMID: 40016271
More than 20% of the population across the world is affected by non-communicable inflammatory skin diseases including psoriasis, atopic dermatitis, hidradenitis suppurativa, rosacea, etc. Many of these chronic diseases are...
7.
Pullen K, Finethy R, Ko S, Reames C, Sassetti C, Lauffenburger D
NPJ Syst Biol Appl . 2025 Feb; 11(1):19. PMID: 39955299
Numerous studies have identified similarities in blood transcriptomic signatures of tuberculosis (TB) phenotypes between mice and humans, including type 1 interferon production and innate immune cell activation. However, murine infection...
8.
Mei S, Li X, Zhou Y, Xu J, Zhang Y, Wan Y, et al.
NPJ Syst Biol Appl . 2025 Feb; 11(1):18. PMID: 39955293
Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung condition characterized by airflow obstruction. Current diagnostic methods primarily rely on identifying prominent features in spirometry (Volume-Flow time series) to detect...
9.
Malik A, Nguyen K, Nardini J, Krona C, Flores K, Nelander S
NPJ Syst Biol Appl . 2025 Feb; 11(1):20. PMID: 39955270
In the study of brain tumors, patient-derived three-dimensional sphere cultures provide an important tool for studying emerging treatments. The growth of such spheroids depends on the combined effects of proliferation...
10.
Golan O, Gampp O, Eckert L, Sauer U
NPJ Syst Biol Appl . 2025 Feb; 11(1):17. PMID: 39929850
Microorganisms primarily utilize nutrients to generate biomass and replicate. When a single nutrient source is available, the produced biomass typically increases linearly with the initial amount of that nutrient. This...