Tamara Delaine
Overview
Explore the profile of Tamara Delaine including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
540
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0
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Recent Articles
1.
Delaine T, Collins P, MacKinnon A, Sharma G, Stegmayr J, Rajput V, et al.
Chembiochem
. 2016 Jun;
17(18):1759-70.
PMID: 27356186
Discovery of glycan-competitive galectin-3-binding compounds that attenuate lung fibrosis in a murine model and that block intracellular galectin-3 accumulation at damaged vesicles, hence revealing galectin-3-glycan interactions involved in fibrosis progression...
2.
Delaine T, Ponting D, Niklasson I, Emter R, Hagvall L, Norrby P, et al.
Chem Res Toxicol
. 2014 Sep;
27(10):1860-70.
PMID: 25195701
Allylic alcohols, such as geraniol 1, are easily oxidized by varying mechanisms, including the formation of both 2,3-epoxides and/or aldehydes. These epoxides, aldehydes, and epoxy-aldehydes can be interconverted to each...
3.
OBoyle N, Niklasson I, Tehrani-Bagha A, Delaine T, Holmberg K, Luthman K, et al.
Chem Res Toxicol
. 2014 May;
27(6):1002-10.
PMID: 24830866
Epoxy resin monomers (ERMs), especially diglycidyl ethers of bisphenol A and F (DGEBA and DGEBF), are extensively used as building blocks for thermosetting polymers. However, they are known to commonly...
4.
Delaine T, Hagvall L, Rudback J, Luthman K, Karlberg A
Chem Res Toxicol
. 2013 Mar;
26(5):674-84.
PMID: 23534857
Structure-activity relationship (SAR) models are important tools for predicting the skin sensitization potential of new compounds without animal testing. In compounds possessing a structural alert (aldehyde) and an activation alert...
5.
Niklasson I, Delaine T, Islam M, Karlsson R, Luthman K, Karlberg A
Contact Dermatitis
. 2013 Feb;
68(3):129-38.
PMID: 23421457
Background: Cinnamyl alcohol and cinnamal are frequent fragrance contact allergens. Both are included in the European baseline fragrance mix I, which is used for screening of contact allergy in dermatitis...
6.
OBoyle N, Delaine T, Luthman K, Natsch A, Karlberg A
Chem Res Toxicol
. 2012 Sep;
25(11):2469-78.
PMID: 22998141
Diglycidyl ethers of bisphenol A (DGEBA) and bisphenol F (DGEBF) are widely used as components in epoxy resin thermosetting products. They are known to cause occupational and nonoccupational allergic contact...
7.
Delaine T, Bernardes-Genisson V, Quemard A, Constant P, Cosledan F, Meunier B, et al.
Chem Biol Drug Des
. 2012 Mar;
79(6):1001-6.
PMID: 22405039
Five lipophilic analogues 1-5 of the active metabolite of the antitubercular drug isoniazid (INH), selected as inhibitors of Mycobacterium smegmatis and Mycobacterium tuberculosis growth, were evaluated for their activity against...
8.
MacKinnon A, Gibbons M, Farnworth S, Leffler H, Nilsson U, Delaine T, et al.
Am J Respir Crit Care Med
. 2011 Nov;
185(5):537-46.
PMID: 22095546
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic dysregulated response to alveolar epithelial injury with differentiation of epithelial cells and fibroblasts into matrix-secreting myofibroblasts resulting in lung scaring. The prognosis...
9.
Delaine T, Niklasson I, Emter R, Luthman K, Karlberg A, Natsch A
Chem Res Toxicol
. 2011 Jul;
24(8):1312-8.
PMID: 21751775
Because of regulatory constraints and ethical considerations, research on alternatives to animal testing to predict the skin sensitization potential of novel chemicals has become a high priority. Ideally, these alternatives...
10.
Niklasson I, Delaine T, Luthman K, Karlberg A
Chem Res Toxicol
. 2011 Mar;
24(4):542-8.
PMID: 21370839
Epoxy resins are among the most common causes of occupational contact dermatitis. They are normally used in so-called epoxy resin systems (ERS). These commercial products are combinations of epoxy resins,...