T Scheuer
Overview
Explore the profile of T Scheuer including associated specialties, affiliations and a list of published articles.
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Articles
86
Citations
4994
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Recent Articles
1.
Rubinstein M, Patowary A, Stanaway I, McCord E, Nesbitt R, Archer M, et al.
Mol Psychiatry
. 2016 Dec;
23(2):231-239.
PMID: 27956748
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder often accompanied by intellectual disability, language impairment and medical co-morbidities. The heritability of autism is high and multiple genes have been...
2.
Anneken V, Hanssen-Doose A, Hirschfeld S, Scheuer T, Thietje R
Spinal Cord
. 2009 Oct;
48(5):393-9.
PMID: 19841634
Study Design: Retrospective cross-sectional study with anonymous postal data collection. Objective: Regaining the best possible mobility and independence is not only the focus of the rehabilitation process for individuals with...
3.
Scheuer T, Catterall W
Biochem Soc Trans
. 2006 Nov;
34(Pt 6):1299-302.
PMID: 17073806
Currents through voltage-gated sodium channels drive action potential depolarization in neurons and other excitable cells. Smaller currents through these channels are key components of currents that control neuronal firing and...
4.
Liu G, Yarov-Yarovoy V, Nobbs M, Clare J, Scheuer T, Catterall W
Neuropharmacology
. 2003 Feb;
44(3):413-22.
PMID: 12604088
Voltage-gated sodium channels are blocked by local anesthetic and anticonvulsant drugs. A receptor site for local anesthetics has been defined in transmembrane segment S6 in domain IV (IVS6) of the...
5.
Qu Y, Curtis R, Lawson D, Gilbride K, Ge P, DiStefano P, et al.
Mol Cell Neurosci
. 2002 Apr;
18(5):570-80.
PMID: 11922146
Brain sodium channels are complexes of a pore-forming alpha subunit with auxiliary beta subunits, which are transmembrane proteins that modulate alpha subunit function. The newly cloned beta3 subunit is shown...
6.
Mantegazza M, Yu F, Catterall W, Scheuer T
Proc Natl Acad Sci U S A
. 2001 Dec;
98(26):15348-53.
PMID: 11742069
Inactivation is a fundamental characteristic of Na(+) channels, and small changes cause skeletal muscle paralysis and myotonia, epilepsy, and cardiac arrhythmia. Brain Na(v)1.2a channels have faster inactivation than cardiac Na(v)1.5...
7.
Cestele S, Scheuer T, Mantegazza M, Rochat H, Catterall W
J Gen Physiol
. 2001 Aug;
118(3):291-302.
PMID: 11524459
beta-Scorpion toxins shift the voltage dependence of activation of sodium channels to more negative membrane potentials, but only after a strong depolarizing prepulse to fully activate the channels. Their receptor...
8.
Zhong H, Li B, Scheuer T, Catterall W
Proc Natl Acad Sci U S A
. 2001 Apr;
98(8):4705-9.
PMID: 11296299
N-type Ca(2+) channels can be inhibited by neurotransmitter-induced release of G protein betagamma subunits. Two isoforms of Ca(v)2.2 alpha1 subunits of N-type calcium channels from rat brain (Ca(v)2.2a and Ca(v)2.2b;...
9.
Herlitze S, Zhong H, Scheuer T, Catterall W
Proc Natl Acad Sci U S A
. 2001 Apr;
98(8):4699-704.
PMID: 11296298
N-type and P/Q-type Ca(2+) channels are inhibited by neurotransmitters acting through G protein-coupled receptors in a membrane-delimited pathway involving Gbetagamma subunits. Inhibition is caused by a shift from an easily...
10.
Hockerman G, Dilmac N, Scheuer T, Catterall W
Mol Pharmacol
. 2000 Nov;
58(6):1264-70.
PMID: 11093762
The benzothiazepine diltiazem blocks ionic current through L-type Ca(2+) channels, as do the dihydropyridines (DHPs) and phenylalkylamines (PAs), but it has unique properties that distinguish it from these other drug...