T S Karin Eisinger-Mathason
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Explore the profile of T S Karin Eisinger-Mathason including associated specialties, affiliations and a list of published articles.
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33
Citations
1289
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Recent Articles
1.
Eisinger-Mathason T, Leshin J, Lahoti V, Fridsma D, Mucaj V, Kho A
Commun Med (Lond)
. 2025 Mar;
5(1):58.
PMID: 40038513
In all fields of study, as well as government and commerce, high-quality data enables informed decision-making. Linking data from disparate sources multiplies the opportunities for novel insights and evidence-based decision-making...
2.
Folkert I, Molina Arocho W, To T, Devalaraja S, Molina I, Shoush J, et al.
J Exp Med
. 2024 Sep;
221(10).
PMID: 39347789
We define a subset of macrophages in the tumor microenvironment characterized by high intracellular iron and enrichment of heme and iron metabolism genes. These iron-rich tumor-associated macrophages (iTAMs) supported angiogenesis...
3.
Fuller A, Pruitt H, Liu Y, Irizarry-Negron V, Pan H, Song H, et al.
J Clin Invest
. 2024 Apr;
134(11).
PMID: 38652549
CD8+ T cell dysfunction impedes antitumor immunity in solid cancers, but the underlying mechanisms are diverse and poorly understood. Extracellular matrix (ECM) composition has been linked to impaired T cell...
4.
Sneider A, Liu Y, Starich B, Du W, Nair P, Marar C, et al.
Cancer Res Commun
. 2024 Apr;
4(5):1240-1252.
PMID: 38630893
Significance: Here we show that the quantity, cargo, and function of breast cancer-derived EVs vary with mechanical properties of the extracellular microenvironment.
5.
Marino-Bravante G, Carey A, Huser L, Dixit A, Wang V, Kaur A, et al.
Nat Aging
. 2024 Mar;
4(3):350-363.
PMID: 38472454
Melanoma, the most lethal form of skin cancer, often has worse outcomes in older patients. We previously demonstrated that an age-related decrease in the secreted extracellular matrix (ECM) protein HAPLN1...
6.
Liu Y, Murazzi I, Fuller A, Pan H, Irizarry-Negron V, DeVine A, et al.
Cancer Res
. 2024 Feb;
84(7):977-993.
PMID: 38335278
Significance: Collagen type VI modified by hypoxia-induced PLOD2 is secreted by sarcoma cells and binds to integrin β1 on endothelial cells to induce barrier dysfunction, which promotes sarcoma vascular dissemination...
7.
Sneider A, Liu Y, Starich B, Du W, Marar C, Faqih N, et al.
bioRxiv
. 2023 Jul;
PMID: 37425743
Tissue stiffness is a critical prognostic factor in breast cancer and is associated with metastatic progression. Here we show an alternative and complementary hypothesis of tumor progression whereby physiological matrix...
8.
Pruitt H, Guan Y, Liu H, Carey A, Brennen W, Lu J, et al.
Matrix Biol
. 2023 Jun;
121:90-104.
PMID: 37331435
The tumor extracellular matrix (ECM) is a barrier to anti-tumor immunity in solid tumors by disrupting T cell-tumor cell interaction underlying the need for elucidating mechanisms by which specific ECM...
9.
10.
Fuller A, DeVine A, Murazzi I, Mason N, Weber K, Eisinger-Mathason T
Cell Oncol (Dordr)
. 2022 Oct;
45(6):1277-1295.
PMID: 36181640
Purpose: Undifferentiated pleomorphic sarcoma (UPS), an aggressive subtype of soft-tissue sarcoma (STS), is exceedingly rare in humans and lacks effective, well-tolerated therapies. In contrast, STS are relatively common in canine...