Svetlana Bezprozvannaya
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Explore the profile of Svetlana Bezprozvannaya including associated specialties, affiliations and a list of published articles.
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35
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2552
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Recent Articles
1.
Gan P, Eppert M, De La Cruz N, Lyons H, Shah A, Veettil R, et al.
Sci Adv
. 2024 Mar;
10(11):eadk7160.
PMID: 38489358
During development, cells make switch-like decisions to activate new gene programs specifying cell lineage. The mechanisms underlying these decisive choices remain unclear. Here, we show that the cardiovascular transcriptional coactivator...
2.
Cui M, Bezprozvannaya S, Hao T, Elnwasany A, Szweda L, Liu N, et al.
Dev Cell
. 2023 Nov;
58(24):2867-2880.e7.
PMID: 37972593
Cardiomyocytes are highly metabolic cells responsible for generating the contractile force in the heart. During fetal development and regeneration, these cells actively divide but lose their proliferative activity in adulthood....
3.
Gan P, Wang Z, Bezprozvannaya S, McAnally J, Tan W, Li H, et al.
Cardiovasc Res
. 2023 Oct;
120(1):56-68.
PMID: 37890031
Aims: RNA binding proteins play essential roles in mediating RNA splicing and are key post-transcriptional regulators in the heart. Our recent study demonstrated that RBPMS (RNA binding protein with multiple...
4.
Dos Santos M, Shah A, Zhang Y, Bezprozvannaya S, Chen K, Xu L, et al.
Nat Commun
. 2023 Jul;
14(1):4333.
PMID: 37468485
Skeletal muscle fibers express distinct gene programs during development and maturation, but the underlying gene regulatory networks that confer stage-specific myofiber properties remain unknown. To decipher these distinctive gene programs...
5.
Makarewich C, Munir A, Bezprozvannaya S, Gibson A, Kim S, Martin-Sandoval M, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(6).
PMID: 35101990
Emerging evidence indicates that a subset of RNA molecules annotated as noncoding contain short open reading frames that code for small functional proteins called microproteins, which have largely been overlooked...
6.
Cannavino J, Shao M, An Y, Bezprozvannaya S, Chen S, Kim J, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(23).
PMID: 34088848
Homeothermic vertebrates produce heat in cold environments through thermogenesis, in which brown adipose tissue (BAT) increases mitochondrial oxidation along with uncoupling of the electron transport chain and activation of uncoupling...
7.
Anderson D, Anderson K, Nelson B, McAnally J, Bezprozvannaya S, Shelton J, et al.
Genes Dev
. 2021 May;
35(11-12):835-840.
PMID: 33985971
Myocardin, a potent coactivator of serum response factor (SRF), competes with ternary complex factor (TCF) proteins for SRF binding to balance opposing mitogenic and myogenic gene programs in cardiac and...
8.
Garry G, Bezprozvannaya S, Chen K, Zhou H, Hashimoto H, Morales M, et al.
Nat Cell Biol
. 2021 May;
23(5):467-475.
PMID: 33941892
Direct cardiac reprogramming of fibroblasts to cardiomyocytes presents an attractive therapeutic strategy to restore cardiac function following injury. Cardiac reprogramming was initially achieved through overexpression of the transcription factors Gata4,...
9.
Makarewich C, Bezprozvannaya S, Gibson A, Bassel-Duby R, Olson E
Circ Res
. 2020 Sep;
127(10):1340-1342.
PMID: 32878549
No abstract available.
10.
Makarewich C, Munir A, Schiattarella G, Bezprozvannaya S, Raguimova O, Cho E, et al.
Elife
. 2018 Oct;
7.
PMID: 30299255
Calcium (Ca) dysregulation is a hallmark of heart failure and is characterized by impaired Ca sequestration into the sarcoplasmic reticulum (SR) by the SR-Ca-ATPase (SERCA). We recently discovered a micropeptide...