Rhonda Bassel-Duby
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Explore the profile of Rhonda Bassel-Duby including associated specialties, affiliations and a list of published articles.
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196
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21638
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Recent Articles
1.
Caputo L, Stamenkovic C, Tierney M, Falzarano M, Bassel-Duby R, Ferlini A, et al.
bioRxiv
. 2024 Dec;
PMID: 39713478
Generation of induced pluripotent cells (hiPSCs)-derived skeletal muscle progenitor cells (SMPCs) holds great promise for regenerative medicine for skeletal muscle wasting diseases, as for example Duchenne Muscular Dystrophy (DMD). Multiple...
2.
A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution
Zhang Y, Dos Santos M, Huang H, Chen K, Iyengar P, Infante R, et al.
Cell Rep
. 2024 Aug;
43(8):114587.
PMID: 39116208
Cancer cachexia is a prevalent and often fatal wasting condition that cannot be fully reversed with nutritional interventions. Muscle atrophy is a central component of the syndrome, but the mechanisms...
3.
Aguilar S, Cui M, Tan W, Sanchez-Ortiz E, Bassel-Duby R, Liu N, et al.
Nat Cardiovasc Res
. 2024 May;
3(3):389-402.
PMID: 38737787
The adult mouse heart responds to injury by scarring with consequent loss of contractile function, whereas the neonatal heart possesses the ability to regenerate. Activation of the immune system is...
4.
Hernandez K, Shah A, Lopez V, Tagliabracci V, Chen K, Xu L, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(4):e2315925121.
PMID: 38227654
Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children and adolescents. Fusion-negative RMS (FN-RMS) accounts for more than 80% of all RMS cases. The long-term event-free...
5.
Cui M, Bezprozvannaya S, Hao T, Elnwasany A, Szweda L, Liu N, et al.
Dev Cell
. 2023 Nov;
58(24):2867-2880.e7.
PMID: 37972593
Cardiomyocytes are highly metabolic cells responsible for generating the contractile force in the heart. During fetal development and regeneration, these cells actively divide but lose their proliferative activity in adulthood....
6.
Stege N, Eijgenraam T, Oliveira Nunes Teixeira V, Feringa A, Schouten E, Kuster D, et al.
Circ Res
. 2023 Nov;
133(12):1006-1021.
PMID: 37955153
Background: The p.Arg14del variant of the (phospholamban) gene causes cardiomyopathy, leading to severe heart failure. Calcium handling defects and perinuclear PLN aggregation have both been suggested as pathological drivers of...
7.
Gan P, Wang Z, Bezprozvannaya S, McAnally J, Tan W, Li H, et al.
Cardiovasc Res
. 2023 Oct;
120(1):56-68.
PMID: 37890031
Aims: RNA binding proteins play essential roles in mediating RNA splicing and are key post-transcriptional regulators in the heart. Our recent study demonstrated that RBPMS (RNA binding protein with multiple...
8.
Lebek S, Caravia X, Straub L, Alzhanov D, Tan W, Li H, et al.
J Clin Invest
. 2023 Oct;
134(1).
PMID: 37856214
Cardiovascular diseases are the most common cause of worldwide morbidity and mortality, highlighting the necessity for advanced therapeutic strategies. Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ) is a prominent inducer of various...
9.
Lebek S, Caravia X, Chemello F, Tan W, McAnally J, Chen K, et al.
Circulation
. 2023 Sep;
148(19):1490-1504.
PMID: 37712250
Background: Cardiovascular diseases are the main cause of worldwide morbidity and mortality, highlighting the need for new therapeutic strategies. Autophosphorylation and subsequent overactivation of the cardiac stress-responsive enzyme CaMKIIδ (Ca/calmodulin-dependent...
10.
Dos Santos M, Shah A, Zhang Y, Bezprozvannaya S, Chen K, Xu L, et al.
Nat Commun
. 2023 Jul;
14(1):4333.
PMID: 37468485
Skeletal muscle fibers express distinct gene programs during development and maturation, but the underlying gene regulatory networks that confer stage-specific myofiber properties remain unknown. To decipher these distinctive gene programs...