Stuart N Farrow
Overview
Explore the profile of Stuart N Farrow including associated specialties, affiliations and a list of published articles.
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29
Citations
1054
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Recent Articles
1.
Chiu C, Willis-Owen S, Wong K, Farrow S, Cookson W, Moffatt M, et al.
J Inflamm (Lond)
. 2024 Jul;
21(1):27.
PMID: 39030600
Background: We have previously discovered clusters of sequentially negative and positive modulators of acute inflammation during cytokine stimulation in epithelial cells and identified potential targets for therapy within these clusters....
2.
Marcellini A, Swieboda D, Guedan A, Farrow S, Casolari P, Contoli M, et al.
Eur J Pharmacol
. 2020 Dec;
893:173839.
PMID: 33359650
Inhaled corticosteroids (ICS) are recommended treatments for all degrees of asthma severity and in combination with bronchodilators are indicated for COPD patients with a history of frequent exacerbations. However, the...
3.
Singh R, Perks W, Twohig J, Kidd E, Broadley K, Farrow S, et al.
Cell Immunol
. 2017 Sep;
320:62-70.
PMID: 28942944
The Death Receptor 3 (DR3)/Tumour Necrosis Factor-like cytokine 1A (TL1A) axis stimulates effector T cells and type 2 innate lymphocytes (ILC2) that trigger cytokine release and drive disease pathology in...
4.
Robertson A, Ogryzko N, Henry K, Loynes C, Foulkes M, Meloni M, et al.
Dis Model Mech
. 2016 Apr;
9(6):621-32.
PMID: 27079522
Neutrophils are essential for host defence and are recruited to sites of inflammation in response to tissue injury or infection. For inflammation to resolve, these cells must be cleared efficiently...
5.
Matthews L, Berry A, Morgan D, Poolman T, Bauer K, Kramer F, et al.
Proc Natl Acad Sci U S A
. 2015 Apr;
112(17):5479-84.
PMID: 25847991
The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily, which controls programs regulating cell proliferation, differentiation, and apoptosis. We have identified an unexpected role for GR in...
6.
Robertson A, Holmes G, Bojarczuk A, Burgon J, Loynes C, Chimen M, et al.
Sci Transl Med
. 2014 Feb;
6(225):225ra29.
PMID: 24574340
Diseases of failed inflammation resolution are common and largely incurable. Therapeutic induction of inflammation resolution is an attractive strategy to bring about healing without increasing susceptibility to infection. However, therapeutic...
7.
Jangani M, Poolman T, Matthews L, Yang N, Farrow S, Berry A, et al.
J Biol Chem
. 2014 Feb;
289(13):8931-46.
PMID: 24488492
Glucocorticoids (GC) regulate cell fate and immune function. We identified the metastasis-promoting methyltransferase, metastasis-related methyltransferase 1 (WBSCR22/Merm1) as a novel glucocorticoid receptor (GR) regulator relevant to human disease. Merm1 binds...
8.
Burgon J, Robertson A, Sadiku P, Wang X, Hooper-Greenhill E, Prince L, et al.
J Immunol
. 2014 Jan;
192(4):1796-805.
PMID: 24431232
The inflammatory response is integral to maintaining health by functioning to resist microbial infection and repair tissue damage. Large numbers of neutrophils are recruited to inflammatory sites to neutralize invading...
9.
Poolman T, Farrow S, Matthews L, Loudon A, Ray D
Nucleic Acids Res
. 2013 Jul;
41(18):8515-25.
PMID: 23887939
The glucocorticoid receptor (GR) is a ligand activated transcription factor, serving to regulate both energy metabolism and immune functions. Factors that influence cellular sensitivity to glucocorticoids (GC) are therefore of...
10.
Durrington H, Farrow S, Loudon A, Ray D
Thorax
. 2013 May;
69(1):90-2.
PMID: 23704227
It is characteristic of asthma that symptoms worsen overnight, particularly in the early hours of the morning. Nocturnal symptoms in asthma are common and are an important indicator for escalation...