Stephen A Renshaw
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Explore the profile of Stephen A Renshaw including associated specialties, affiliations and a list of published articles.
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109
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4069
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Recent Articles
1.
Tooke A, Hodges R, Pyrah J, Bayles K, Renshaw S, Foster S
Curr Microbiol
. 2024 Nov;
81(12):447.
PMID: 39505760
Oxacillin (bactericidal) and tetracycline (bacteriostatic) are clinically relevant antibiotics that are routinely prescribed to treat Staphylococcus aureus infections but not conventionally used in combination. There is an urgent need for...
2.
Rutherford H, Candeias D, Duncan C, Renshaw S, Hamilton N
Proc Natl Acad Sci U S A
. 2024 May;
121(21):e2321496121.
PMID: 38753517
RNASET2-deficient leukodystrophy is a rare infantile white matter disorder mimicking a viral infection and resulting in severe psychomotor impairments. Despite its severity, there is little understanding of cellular mechanisms of...
3.
Alves J, Vrieling M, Ring N, Yebra G, Pickering A, Prajsnar T, et al.
mBio
. 2024 Apr;
15(6):e0034624.
PMID: 38682911
Importance: is an important human bacterial pathogen. The host response to involves the production of innate immune cells such as macrophages which are important for fighting infection. Here we report...
4.
Speirs Z, Loynes C, Mathiessen H, Elks P, Renshaw S, Jorgensen L
Fish Shellfish Immunol
. 2024 Mar;
148:109490.
PMID: 38471626
Fish rely, to a high degree, on the innate immune system to protect them against the constant exposure to potential pathogenic invasion from the surrounding water during homeostasis and injury....
5.
Hibbert T, Whiteley M, Renshaw S, Neill D, Fothergill J
Crit Rev Microbiol
. 2023 Nov;
50(6):1037-1052.
PMID: 37999716
is an opportunistic pathogen that is responsible for infections in people living with chronic respiratory conditions, such as cystic fibrosis (CF) and non-CF bronchiectasis (NCFB). Traditionally, in people with chronic...
6.
Jubber I, Morhardt D, Griffin J, Cumberbatch M, Glover M, Zheng Y, et al.
Dis Model Mech
. 2023 Jun;
16(7).
PMID: 37293698
Little is known about the distal excretory component of the urinary tract in Danio rerio (zebrafish). This component is affected by many human diseases and disorders of development. Here, we...
7.
Morsli S, Henriques C, Ellis P, Mortiboys H, Baxendale S, Loynes C, et al.
Aging Cell
. 2023 Apr;
22(6):e13835.
PMID: 37039087
Senescence drives the onset and severity of multiple ageing-associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and in the search for compounds...
8.
Elworthy S, Rutherford H, Prajsnar T, Hamilton N, Vogt K, Renshaw S, et al.
Dis Model Mech
. 2023 Feb;
16(3).
PMID: 36805642
People with activated PI3 kinase delta syndrome 1 (APDS1) suffer from immune deficiency and severe bronchiectasis. APDS1 is caused by dominant activating mutations of the PIK3CD gene that encodes the...
9.
Pidwill G, Pyrah J, Sutton J, Best A, Renshaw S, Foster S
Sci Rep
. 2023 Jan;
13(1):1188.
PMID: 36681703
Staphylococcus aureus is a human commensal and also an opportunist pathogen causing life threatening infections. During S. aureus disease, the abscesses that characterise infection can be clonal, whereby a large...
10.
Herman K, Wright C, Marriott H, McCaughran S, Bowden K, Collins M, et al.
Front Immunol
. 2022 Aug;
13:956991.
PMID: 35967296
Dysregulated neutrophilic inflammation can be highly destructive in chronic inflammatory diseases due to prolonged neutrophil lifespan and continual release of histotoxic mediators in inflamed tissues. Therapeutic induction of neutrophil apoptosis,...