Stuart A Nicklin
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Explore the profile of Stuart A Nicklin including associated specialties, affiliations and a list of published articles.
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76
Citations
3070
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Recent Articles
1.
McFall A, Graham D, Nicklin S, Work L
Brain Neurosci Adv
. 2024 Mar;
8:23982128241238934.
PMID: 38516557
Ischaemic stroke presents a significant problem worldwide with no neuroprotective drugs available. Many of the failures in the search for neuroprotectants are attributed to failure to translate from pre-clinical models...
2.
Martin T, MacDonald E, Bradley A, Watson H, Saxena P, Rog-Zielinska E, et al.
Cardiovasc Res
. 2023 Jul;
119(16):2663-2671.
PMID: 37433039
Aims: Myocardial infarction (MI) is a major cause of death worldwide. Effective treatments are required to improve recovery of cardiac function following MI, with the aim of improving patient outcomes...
3.
Divorty N, Jenkins L, Ganguly A, Butcher A, Hudson B, Schulz S, et al.
J Biol Chem
. 2022 Feb;
298(3):101655.
PMID: 35101446
G protein-coupled receptor 35 (GPR35) is poorly characterized but nevertheless has been revealed to have diverse roles in areas including lower gut inflammation and pain. The development of novel reagents...
4.
In Vitro and In Vivo Evaluation of Human Adenovirus Type 49 as a Vector for Therapeutic Applications
Bates E, Counsell J, Alizert S, Baker A, Suff N, Boyle A, et al.
Viruses
. 2021 Aug;
13(8).
PMID: 34452348
The human adenovirus phylogenetic tree is split across seven species (A-G). Species D adenoviruses offer potential advantages for gene therapy applications, with low rates of pre-existing immunity detected across screened...
5.
He W, McCarroll C, Nather K, Ford K, Mangion K, Riddell A, et al.
Cardiovasc Res
. 2021 Jun;
118(6):1535-1547.
PMID: 34132807
Aims: Identifying novel mediators of lethal myocardial reperfusion injury that can be targeted during primary percutaneous coronary intervention (PPCI) is key to limiting the progression of patients with ST-elevation myocardial...
6.
Martin T, MacDonald E, Elbassioni A, OToole D, Zaeri A, Nicklin S, et al.
Br J Pharmacol
. 2021 Jun;
179(5):770-791.
PMID: 34131903
Approximately 7 million people are affected by acute myocardial infarction (MI) each year, and despite significant therapeutic and diagnostic advancements, MI remains a leading cause of mortality worldwide. Preclinical animal...
7.
McFall A, Nicklin S, Work L
Cell Signal
. 2020 Oct;
76:109809.
PMID: 33059037
Stroke is the 2nd leading cause of death worldwide and the leading cause of physical disability and cognitive issues. Although we have made progress in certain aspects of stroke treatment,...
8.
OToole D, Zaeri A, Nicklin S, French A, Loughrey C, Martin T
Cell Signal
. 2020 Sep;
76:109770.
PMID: 32891693
Adverse cardiac remodelling clinically manifests as deleterious changes to heart architecture (size, mass and geometry) and function. These changes, which include alterations to ventricular wall thickness, chamber dilation and poor...
9.
Guzik T, Mohiddin S, Dimarco A, Patel V, Savvatis K, Marelli-Berg F, et al.
Cardiovasc Res
. 2020 May;
116(10):1666-1687.
PMID: 32352535
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents the greatest medical challenge in decades. We provide a comprehensive review of the clinical course of COVID-19, its comorbidities, and...
10.
Riddell A, McBride M, Braun T, Nicklin S, Cameron E, Loughrey C, et al.
Cardiovasc Res
. 2020 Mar;
116(8):1410-1423.
PMID: 32154891
Runt-related transcription factor-1 (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription factors which modulate cell proliferation, differentiation, and...