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Angela C Bradshaw

Explore the profile of Angela C Bradshaw including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 796
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Recent Articles
1.
Bates E, Counsell J, Alizert S, Baker A, Suff N, Boyle A, et al.
Viruses . 2021 Aug; 13(8). PMID: 34452348
The human adenovirus phylogenetic tree is split across seven species (A-G). Species D adenoviruses offer potential advantages for gene therapy applications, with low rates of pre-existing immunity detected across screened...
2.
Monteiro J, Rodor J, Caudrillier A, Scanlon J, Spiroski A, Dudnakova T, et al.
Circ Res . 2021 Mar; 128(8):1173-1190. PMID: 33703914
[Figure: see text].
3.
Mahmoud A, Ballantyne M, Miscianinov V, Pinel K, Hung J, Scanlon J, et al.
Circ Res . 2019 Jul; 125(5):535-551. PMID: 31339449
Rationale: In response to blood vessel wall injury, aberrant proliferation of vascular smooth muscle cells (SMCs) causes pathological remodeling. However, the controlling mechanisms are not completely understood. Objective: We recently...
4.
Noonan J, Grassia G, MacRitchie N, Garside P, Guzik T, Bradshaw A, et al.
Front Immunol . 2019 May; 10:849. PMID: 31068936
Atherosclerosis is a complex inflammatory pathology underpinning cardiovascular diseases (CVD), which are the leading cause of death worldwide. The interplay between vascular stromal cells and immune cells is fundamental to...
5.
Noonan J, Asiala S, Grassia G, MacRitchie N, Gracie K, Carson J, et al.
Theranostics . 2019 Jan; 8(22):6195-6209. PMID: 30613292
Vascular immune-inflammatory responses play a crucial role in the progression and outcome of atherosclerosis. The ability to assess localized inflammation through detection of specific vascular inflammatory biomarkers would significantly improve...
6.
Low E, Baker A, Bradshaw A
Cell Signal . 2018 Sep; 53:90-101. PMID: 30227237
Excessive vascular smooth muscle cell (SMC) proliferation, migration and extracellular matrix (ECM) synthesis are key events in the development of intimal hyperplasia, a pathophysiological response to acute or chronic sources...
7.
Lopez-Gordo E, Doszpoly A, Duffy M, Coughlan L, Bradshaw A, White K, et al.
J Virol . 2017 Apr; 91(12). PMID: 28381574
Human adenoviral serotype 5 (HAdV-5) vectors have predominantly hepatic tropism when delivered intravascularly, resulting in immune activation and toxicity. Coagulation factor X (FX) binding to HAdV-5 mediates liver transduction and...
8.
Deng L, Baker A, Bradshaw A
Methods Mol Biol . 2016 Dec; 1521:325-338. PMID: 27910060
Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation of pulmonary artery smooth muscle cells and endothelial cells associated with obliteration of small pulmonary arterioles and formation of plexiform lesions....
9.
Deng L, Bradshaw A, Baker A
Curr Opin Lipidol . 2016 Jul; 27(5):439-48. PMID: 27472407
Purpose Of Review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling. We highlight recent...
10.
Deng L, Blanco F, Stevens H, Lu R, Caudrillier A, McBride M, et al.
Circ Res . 2015 Aug; 117(10):870-883. PMID: 26311719
Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) remains unclear. The 4 microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered. Objective: To elucidate the transcriptional regulation of...