Christopher M Loughrey
Overview
Explore the profile of Christopher M Loughrey including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
454
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0
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Recent Articles
1.
Kaneko N, Loughrey C, Smith G, Matsuda R, Hasunuma T, Mark P, et al.
Br J Pharmacol
. 2024 May;
181(18):3401-3419.
PMID: 38773354
Background And Purpose: The ryanodine receptor 2 (RyR2) is present in both the heart and kidneys, and plays a crucial role in maintaining intracellular Ca homeostasis in cells in these...
2.
Martin T, MacDonald E, Bradley A, Watson H, Saxena P, Rog-Zielinska E, et al.
Cardiovasc Res
. 2023 Jul;
119(16):2663-2671.
PMID: 37433039
Aims: Myocardial infarction (MI) is a major cause of death worldwide. Effective treatments are required to improve recovery of cardiac function following MI, with the aim of improving patient outcomes...
3.
He W, McCarroll C, Nather K, Ford K, Mangion K, Riddell A, et al.
Cardiovasc Res
. 2021 Jun;
118(6):1535-1547.
PMID: 34132807
Aims: Identifying novel mediators of lethal myocardial reperfusion injury that can be targeted during primary percutaneous coronary intervention (PPCI) is key to limiting the progression of patients with ST-elevation myocardial...
4.
Martin T, MacDonald E, Elbassioni A, OToole D, Zaeri A, Nicklin S, et al.
Br J Pharmacol
. 2021 Jun;
179(5):770-791.
PMID: 34131903
Approximately 7 million people are affected by acute myocardial infarction (MI) each year, and despite significant therapeutic and diagnostic advancements, MI remains a leading cause of mortality worldwide. Preclinical animal...
5.
OToole D, Zaeri A, Nicklin S, French A, Loughrey C, Martin T
Cell Signal
. 2020 Sep;
76:109770.
PMID: 32891693
Adverse cardiac remodelling clinically manifests as deleterious changes to heart architecture (size, mass and geometry) and function. These changes, which include alterations to ventricular wall thickness, chamber dilation and poor...
6.
Mangion K, Loughrey C, Auger D, McComb C, Lee M, Corcoran D, et al.
J Magn Reson Imaging
. 2020 Jul;
52(6):1722-1731.
PMID: 32720405
Background: Segmental extent of infarction assessed by late gadolinium enhancement (LGE) imaging early post-ST-segment elevation myocardial infarction (STEMI) has utility in predicting left ventricular functional recovery. Hypothesis: We hypothesized that...
7.
Riddell A, McBride M, Braun T, Nicklin S, Cameron E, Loughrey C, et al.
Cardiovasc Res
. 2020 Mar;
116(8):1410-1423.
PMID: 32154891
Runt-related transcription factor-1 (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription factors which modulate cell proliferation, differentiation, and...
8.
Guzik T, Antoniades C, Baker A, Harrison D, Loughrey C, Maffia P, et al.
Cardiovasc Res
. 2019 Jan;
114(12):1565-1568.
PMID: 30629152
No abstract available.
9.
McCarroll C, He W, Foote K, Bradley A, McGlynn K, Vidler F, et al.
Circulation
. 2017 Oct;
137(1):57-70.
PMID: 29030345
Background: Myocardial infarction (MI) is a leading cause of heart failure and death worldwide. Preservation of contractile function and protection against adverse changes in ventricular architecture (cardiac remodeling) are key...
10.
Ross P, Guy J, Selfridge J, Kamal B, Bahey N, Tanner K, et al.
Hum Mol Genet
. 2017 Feb;
25(20):4389-4404.
PMID: 28173151
Rett syndrome (RTT) is a severe genetic disorder resulting from mutations in the X-linked MECP2 gene. MeCP2 protein is highly expressed in the nervous system and deficiency in the mouse...