Steven Watterson
Overview
Explore the profile of Steven Watterson including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1263
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Recent Articles
11.
Joshi A, Wang D, Watterson S, McClean P, Behera C, Sharp T, et al.
Neuropharmacology
. 2020 May;
174:108118.
PMID: 32380022
Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is characterised by abnormal accumulation of beta-amyloid...
12.
McGilligan V, Watterson S, Rjoob K, Chemaly M, Bond R, Iftikhar A, et al.
J Electrocardiol
. 2019 Sep;
57S:S92-S97.
PMID: 31519392
Background: Acute Coronary Syndrome (ACS) is currently diagnosed using a 12‑lead Electrocardiogram (ECG). Our recent work however has shown that interpretation of the 12‑lead ECG is complex and that clinicians...
13.
McLaughlin J, Watterson S, Layton A, Bjourson A, Barnard E, McDowell A
Microorganisms
. 2019 May;
7(5).
PMID: 31086023
The anaerobic bacterium is believed to play an important role in the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our understanding of the taxonomic...
14.
Parton A, McGilligan V, Chemaly M, OKane M, Watterson S
Bioinformatics
. 2018 Dec;
35(14):2449-2457.
PMID: 30520978
Motivation: Atherosclerosis is amongst the leading causes of death globally. However, it is challenging to study in vivo or in vitro and no detailed, openly-available computational models exist. Clinical studies...
15.
Mazein A, Ostaszewski M, Kuperstein I, Watterson S, Le Novere N, Lefaudeux D, et al.
NPJ Syst Biol Appl
. 2018 Jun;
4:21.
PMID: 29872544
The development of computational approaches in systems biology has reached a state of maturity that allows their transition to systems medicine. Despite this progress, intuitive visualisation and context-dependent knowledge representation...
16.
Chemaly M, McGilligan V, Gibson M, Clauss M, Watterson S, Alexander H, et al.
Arch Cardiovasc Dis
. 2017 Nov;
110(12):700-711.
PMID: 29097110
Tumour necrosis factor alpha converting enzyme (TACE/ADAM17) is a member of the A disintegrin and metalloproteinase (ADAM) family of ectodomain shedding proteinases. It regulates many inflammatory processes by cleaving several...
17.
Benson H, Watterson S, Sharman J, Mpamhanga C, Parton A, Southan C, et al.
Br J Pharmacol
. 2017 Sep;
174(23):4362-4382.
PMID: 28910500
Background And Purpose: An ever-growing wealth of information on current drugs and their pharmacological effects is available from online databases. As our understanding of systems biology increases, we have the...
18.
19.
Henderson R, OKane M, McGilligan V, Watterson S
J Biomed Sci
. 2016 Apr;
23:39.
PMID: 27084339
Familial Hypercholesterolaemia is an autosomal, dominant genetic disorder that leads to elevated blood cholesterol and a dramatically increased risk of atherosclerosis. It is perceived as a rare condition. However it...
20.
Robertson K, Hsieh W, Forster T, Blanc M, Lu H, Crick P, et al.
PLoS Biol
. 2016 Mar;
14(3):e1002364.
PMID: 26938778
In invertebrates, small interfering RNAs are at the vanguard of cell-autonomous antiviral immunity. In contrast, antiviral mechanisms initiated by interferon (IFN) signaling predominate in mammals. Whilst mammalian IFN-induced miRNA are...