Briefings in Bioinformatics
Overview
Briefings in Bioinformatics is a renowned peer-reviewed journal that provides concise and up-to-date reviews, perspectives, and analyses on the latest advancements in bioinformatics. Covering a wide range of topics, it offers valuable insights into the application of computational methods and tools in biological research, genomics, proteomics, and systems biology. With its succinct format, the journal serves as an essential resource for researchers, practitioners, and students in the field of bioinformatics.
Details
Details
Abbr.
Brief Bioinform
Publisher
Oxford University Press
Start
2000
End
Continuing
Frequency
Bimonthly, 2007-
p-ISSN
1467-5463
e-ISSN
1477-4054
Country
United Kingdom
Language
English
Specialty
Biology
Metrics
Metrics
h-index / Ranks: 1584
142
SJR / Ranks: 1059
2143
CiteScore / Ranks: 1186
10.90
JIF / Ranks: 503
9.5
Recent Articles
1.
Qiu S, Hu B, Zhao J, Xu W, Yang A
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40079266
An accurate deep learning predictor is needed for enzyme optimal temperature (${T}_{opt}$), which quantitatively describes how temperature affects the enzyme catalytic activity. In comparison with existing models, a new model...
2.
Burger N, Nicolis V, Botha A
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40079265
Aphids are a speciose family of the Hemiptera compromising >5500 species. They have adapted to feed off multiple plant species and occur on every continent on Earth. Although economically devastating,...
3.
Sereshki S, Lonardi S
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40079264
DNA methylation is an epigenetic marker that directly or indirectly regulates several critical cellular processes. While cytosines in mammalian genomes generally maintain stable methylation patterns over time, other cytosines that...
4.
Huusari R, Wang T, Szedmak S, Dias D, Aittokallio T, Rousu J
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40079263
Drug combinations are required to treat advanced cancers and other complex diseases. Compared with monotherapy, combination treatments can enhance efficacy and reduce toxicity by lowering the doses of single drugs-and...
5.
Li Y, Pan X, Shen H, Yang Y
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40079262
The rapid development of RNA vaccines and therapeutics puts forward intensive requirements on the sequence design of RNAs. RNA sequence design, or RNA inverse folding, aims to generate RNA sequences...
6.
Zeng H, Yin C, Chai C, Wang Y, Dai Q, Sun H
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40072848
Identifying genes causally linked to cancer from a multi-omics perspective is essential for understanding the mechanisms of cancer and improving therapeutic strategies. Traditional statistical and machine-learning methods that rely on...
7.
Nguyen H, Kim W
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40072847
This work aims to (1) identify microbial and metabolic alterations and (2) reveal a shift in phenylalanine production-consumption equilibrium in individuals with HIV. We conducted extensive searches in multiple databases...
8.
Qi Y, Wang X, Qin L
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40072846
Accurate sample classification using transcriptomics data is crucial for advancing personalized medicine. Achieving this goal necessitates determining a suitable sample size that ensures adequate classification accuracy without undue resource allocation....
9.
Mao R, Wan L, Zhou M, Li D
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40067266
High-throughput sequencing technologies have facilitated a deeper exploration of prognostic biomarkers. While many deep learning (DL) methods primarily focus on feature extraction or employ simplistic fully connected layers within prognostic...
10.
Dobson L, Tusnady G, Tompa P
Brief Bioinform
. 2025 Mar;
26(2).
PMID: 40067116
AlphaFold2 changed structural biology by providing high-quality structure predictions for all possible proteins. Since its inception, a plethora of applications were built on AlphaFold2, expediting discoveries in virtually all areas...