Steven P Williams
Overview
Explore the profile of Steven P Williams including associated specialties, affiliations and a list of published articles.
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16
Citations
786
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Recent Articles
1.
Thomas L, Esposito C, Morgan R, Price S, Young J, Williams S, et al.
Commun Biol
. 2021 May;
4(1):615.
PMID: 34021238
Mitochondria are typically essential for the viability of eukaryotic cells, and utilize oxygen and nutrients (e.g. glucose) to perform key metabolic functions that maintain energetic homeostasis and support proliferation. Here...
2.
Karnezis T, Farnsworth R, Harris N, Williams S, Caesar C, Byrne D, et al.
Cancer Res
. 2019 Feb;
79(7):1558-1572.
PMID: 30709930
Metastasis via the lymphatic vasculature is an important step in cancer progression. The formation of new lymphatic vessels (lymphangiogenesis), or remodeling of existing lymphatics, is thought to facilitate the entry...
3.
Williams S, Barthorpe A, Lightfoot H, Garnett M, McDermott U
Sci Data
. 2018 Oct;
5:180215.
PMID: 30299440
This corrects the article DOI: 10.1038/sdata.2017.139.
4.
Williams S, Odell A, Karnezis T, Farnsworth R, Gould C, Li J, et al.
Sci Signal
. 2017 Oct;
10(499).
PMID: 28974649
Lymphatic vessels constitute a specialized vasculature that is involved in development, cancer, obesity, and immune regulation. The migration of lymphatic endothelial cells (LECs) is critical for vessel growth (lymphangiogenesis) and...
5.
Williams S, Barthorpe A, Lightfoot H, Garnett M, McDermott U
Sci Data
. 2017 Oct;
4:170139.
PMID: 28972570
Metastatic colorectal cancer is a leading cause of cancer death. However, current therapy options are limited to chemotherapy, with the addition of anti-EGFR antibodies for patients with RAS wild-type tumours....
6.
Roumeliotis T, Williams S, Goncalves E, Alsinet C, Del Castillo Velasco-Herrera M, Aben N, et al.
Cell Rep
. 2017 Aug;
20(9):2201-2214.
PMID: 28854368
Assessing the impact of genomic alterations on protein networks is fundamental in identifying the mechanisms that shape cancer heterogeneity. We have used isobaric labeling to characterize the proteomic landscapes of...
7.
Williams S, McDermott U
Cell Chem Biol
. 2017 Jul;
24(9):1066-1074.
PMID: 28736238
In the last decade we have witnessed tremendous advances in our understanding of the landscape of the molecular alterations that underpin many of the most prevalent cancers, in the use...
8.
Williams S, Gould C, Nowell C, Karnezis T, Achen M, Simpson K, et al.
Sci Data
. 2017 Mar;
4:170009.
PMID: 28248931
Many cell types undergo migration during embryogenesis and disease. Endothelial cells line blood vessels and lymphatics, which migrate during development as part of angiogenesis, lymphangiogenesis and other types of vessel...
9.
Brammeld J, Petljak M, Martincorena I, Williams S, Alonso L, Dalmases A, et al.
Genome Res
. 2017 Feb;
27(4):613-625.
PMID: 28179366
Drug resistance is an almost inevitable consequence of cancer therapy and ultimately proves fatal for the majority of patients. In many cases, this is the consequence of specific gene mutations...
10.
Gambino T, Williams S, Caesar C, Resnick D, Nowell C, Farnsworth R, et al.
Assay Drug Dev Technol
. 2017 Jan;
15(1):30-43.
PMID: 28092460
The lymphatic system is a series of vessels that transport cells and excess fluid from tissues to the blood vascular system. Normally quiescent, the lymphatics can grow or remodel in...