Tara Karnezis
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Explore the profile of Tara Karnezis including associated specialties, affiliations and a list of published articles.
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42
Citations
1827
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Recent Articles
1.
Yuan Y, Levy S, Yeo Y, Shayan R, Karnezis T, Stacker S, et al.
iScience
. 2025 Mar;
28(3):111948.
PMID: 40060910
Secondary lymphedema is a debilitating chronic tissue swelling in a limb caused by inadequate interstitial fluid drainage due to dysfunctional lymphatic vessels. Pathological enlargement of small lymphatics contributes to lymphatic...
2.
Morgan S, Reid I, Bendon C, Ishaq M, Shayan R, Pope B, et al.
Lymphat Res Biol
. 2024 Feb;
22(2):106-111.
PMID: 38407896
Lipedema is a progressive condition involving excessive deposition of subcutaneous adipose tissue, predominantly in the lower limbs, which severely compromises quality of life. Despite the impact of lipedema, its molecular...
3.
Bendon C, Hanssen E, Nowell C, Karnezis T, Shayan R
Plast Reconstr Surg Glob Open
. 2024 Jan;
12(1):e5547.
PMID: 38268719
Background: Lymphedema is common after lymphatic damage in cancer treatment, with negative impacts on function and quality of life. Evidence suggests that blood vessel microvasculature is sensitive to irradiation and...
4.
Pillay V, Shukla L, Herle P, Maciburko S, Bandara N, Reid I, et al.
Front Pharmacol
. 2023 May;
14:1152314.
PMID: 37188266
Surgery and radiotherapy are key cancer treatments and the leading causes of damage to the lymphatics, a vascular network critical to fluid homeostasis and immunity. The clinical manifestation of this...
5.
Tuohinto K, DiMaio T, Kiss E, Laakkonen P, Saharinen P, Karnezis T, et al.
PLoS Pathog
. 2023 Jan;
19(1):e1010753.
PMID: 36689549
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS. While spindle...
6.
Shuka L, Lee S, Du M, Karnezis T, Ritchie M, Shayan R
Data Brief
. 2022 Jun;
43:108358.
PMID: 35761990
[This corrects the article DOI: 10.1016/j.dib.2022.107828.].
7.
Shukla L, Lee S, Du M, Karnezis T, Ritchie M, Shayan R
Data Brief
. 2022 Feb;
41:107828.
PMID: 35127999
Radiotherapy injury to cells of the skin and subcutaneous tissue is an inevitable consequence of external beam radiation for treatment of cancer. This sublethal injury to normal tissues plays a...
8.
Seebauer C, Graus M, Huang L, McCann A, Wylie-Sears J, Fontaine F, et al.
J Clin Invest
. 2021 Dec;
132(3).
PMID: 34874911
Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are composed of R(+) and S(-) enantiomers: the R(+) enantiomer is largely devoid of beta blocker activity. We investigated the...
9.
Ishaq M, Bandara N, Morgan S, Nowell C, Mehdi A, Lyu R, et al.
Int J Obes (Lond)
. 2021 Nov;
46(3):502-514.
PMID: 34764426
Objectives: Lipedema, a poorly understood chronic disease of adipose hyper-deposition, is often mistaken for obesity and causes significant impairment to mobility and quality-of-life. To identify molecular mechanisms underpinning lipedema, we...
10.
Shukla L, Luwor R, Ritchie M, Akbarzadeh S, Zhu H, Morrison W, et al.
Plast Reconstr Surg Glob Open
. 2020 Jun;
8(3):e2706.
PMID: 32537359
Methods: To investigate cellular changes resulting in the fibrotic side-effects of RTx, cultured normal human dermal fibroblasts (NHDF) were irradiated (10Gy), then studied using functional assays that reflect key fibroblast...