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Steven A Stacker

Explore the profile of Steven A Stacker including associated specialties, affiliations and a list of published articles. Areas
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Articles 101
Citations 4576
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Recent Articles
1.
Yuan Y, Levy S, Yeo Y, Shayan R, Karnezis T, Stacker S, et al.
iScience . 2025 Mar; 28(3):111948. PMID: 40060910
Secondary lymphedema is a debilitating chronic tissue swelling in a limb caused by inadequate interstitial fluid drainage due to dysfunctional lymphatic vessels. Pathological enlargement of small lymphatics contributes to lymphatic...
2.
Pillay V, Shukla L, Herle P, Maciburko S, Bandara N, Reid I, et al.
Front Pharmacol . 2023 May; 14:1152314. PMID: 37188266
Surgery and radiotherapy are key cancer treatments and the leading causes of damage to the lymphatics, a vascular network critical to fluid homeostasis and immunity. The clinical manifestation of this...
3.
Bai Y, Gotz C, Chincarini G, Zhao Z, Slaney C, Boath J, et al.
Nat Commun . 2023 Mar; 14(1):1591. PMID: 36949044
In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are currently missing. An integrated analysis of patient HNC subtypes using single-cell sequencing and proteome profiles reveals an epithelial-mesenchymal transition...
4.
Cucanic O, Farnsworth R, Stacker S
Growth Factors . 2022 Jul; 40(3-4):119-152. PMID: 35861197
Organ-specific metastasis to secondary organs is dependent on the formation of a supportive pre-metastatic niche. This tissue-specific microenvironmental response is thought to be mediated by mutational and epigenetic changes to...
5.
Tobar L, Farnsworth R, Stacker S
Biomolecules . 2022 Mar; 12(3). PMID: 35327593
Primary tumours, particularly from major solid organs, are able to disseminate into the blood and lymphatic system and spread to distant sites. These secondary metastases to other major organs are...
6.
He M, Halford M, Liu R, Roy J, Grant Z, Coultas L, et al.
Commun Biol . 2021 Jul; 4(1):878. PMID: 34267311
Angiogenesis underlies development, physiology and pathogenesis of cancer, eye and cardiovascular diseases. Inhibiting aberrant angiogenesis using anti-angiogenic therapy (AAT) has been successful in the clinical treatment of cancer and eye...
7.
Chau T, Baek S, Coxam B, Skoczylas R, Rondon-Galeano M, Bower N, et al.
Dev Dyn . 2021 Jun; 251(2):336-349. PMID: 34174014
Background: Lymphatic vascular development is regulated by well-characterized signaling and transcriptional pathways. These pathways regulate lymphatic endothelial cell (LEC) migration, motility, polarity, and morphogenesis. Canonical and non-canonical WNT signaling pathways...
8.
Arcucci V, Stacker S, Achen M
Biomolecules . 2021 Feb; 11(2). PMID: 33572413
Tumour angiogenesis and lymphangiogenesis are hallmarks of cancer and have been associated with tumour progression, tumour metastasis and poor patient prognosis. Many factors regulate angiogenesis and lymphangiogenesis in cancer including...
9.
Wang S, Roy J, Tomlinson A, Wang E, Tsai Y, Cameron L, et al.
Development . 2020 Sep; 147(20). PMID: 32994164
Between embryonic days 10.5 and 14.5, active proliferation drives rapid elongation of the murine midgut epithelial tube. Within this pseudostratified epithelium, nuclei synthesize DNA near the basal surface and move...
10.