Stephane Sarrazin
Overview
Explore the profile of Stephane Sarrazin including associated specialties, affiliations and a list of published articles.
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16
Citations
977
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Recent Articles
11.
Sarrazin S, Lyon M, Deakin J, Guerrini M, Lassalle P, Delehedde M, et al.
Glycobiology
. 2010 Jun;
20(11):1380-8.
PMID: 20581009
Endocan is a recently identified soluble chondroitin/dermatan sulfate (CS/DS) proteoglycan. Synthesized by endothelial cells, it has been found to be over-expressed in the vasculature surrounding a number of tumors, and...
12.
Sarrazin S, Wilson B, Sly W, Tor Y, Esko J
Mol Ther
. 2010 May;
18(7):1268-74.
PMID: 20442709
Guanidinylated neomycin (GNeo) can transport bioactive, high molecular weight cargo into the interior of cells in a process that depends on cell surface heparan sulfate proteoglycans. In this report, we...
13.
Maurage C, Adam E, Mineo J, Sarrazin S, Debunne M, Siminski R, et al.
J Neuropathol Exp Neurol
. 2009 May;
68(6):633-41.
PMID: 19458546
Glioblastomas (GBMs) are highly malignant tumors characterized by microvascular proliferation and the pseudopalisading pattern of necrosis. Investigations have, therefore, focused on vascular and endothelial cell biology in GBM. Endocan, also...
14.
Adam E, Sarrazin S, Landolfi C, Motte V, Lortat-Jacob H, Lassalle P, et al.
Biochem Biophys Res Commun
. 2008 Feb;
369(2):297-302.
PMID: 18261977
Standard culture systems of eukaryotic cells generally failed to deliver sufficient amounts of recombinant proteins without increasing the costs of production. We here showed that membrane-based bioreactors, initially developed for...
15.
Sarrazin S, Bonnaffe D, Lubineau A, Lortat-Jacob H
J Biol Chem
. 2005 Sep;
280(45):37558-64.
PMID: 16155294
Cell-associated heparan sulfate (HS) is endowed with the remarkable ability to bind numerous proteins. As such, it represents a unique system that integrates signaling from circulating ligands with cellular receptors....
16.
Lubineau A, Lortat-Jacob H, Gavard O, Sarrazin S, Bonnaffe D
Chemistry
. 2004 Sep;
10(17):4265-82.
PMID: 15352109
We have recently described the preparation of three building blocks for the combinatorial synthesis of heparan sulfate (HS) fragments. Herein we show that one of these building blocks (disaccharide 4)...