Sriram Sundaravel
Overview
Explore the profile of Sriram Sundaravel including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
204
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Taylor S, Stauber J, Bohorquez O, Tatsumi G, Kumari R, Chakraborty J, et al.
Nat Genet
. 2024 Sep;
56(10):2213-2227.
PMID: 39294495
Transcription factor (TF) DNA-binding dynamics govern cell fate and identity. However, our ability to pharmacologically control TF localization is limited. Here we leverage chemically driven binding site restriction leading to...
2.
Kao Y, Chen J, Kumari R, Ng A, Zintiridou A, Tatiparthy M, et al.
Cell Stem Cell
. 2024 Feb;
31(3):378-397.e12.
PMID: 38402617
Mechanisms governing the maintenance of blood-producing hematopoietic stem and multipotent progenitor cells (HSPCs) are incompletely understood, particularly those regulating fate, ensuring long-term maintenance, and preventing aging-associated stem cell dysfunction. We...
3.
Piszczatowski R, Schwenger E, Sundaravel S, Stein C, Liu Y, Stanley P, et al.
J Exp Med
. 2022 Sep;
219(11).
PMID: 36066492
Cell surfaces display a wide array of molecules that confer identity. While flow cytometry and cluster of differentiation (CD) markers have revolutionized cell characterization and purification, functionally heterogeneous cellular subtypes...
4.
Taylor S, Sundaravel S, Steidl U
Mol Cell
. 2021 Sep;
81(17):3445-3446.
PMID: 34478652
In this issue of Molecular Cell, Cao et al. (2021) report that AML cells are specifically addicted to an IRF8-MEF2D gene expression network. Furthermore, they identify a chromatin reader, ZMYND8,...
5.
Sundaravel S, Steidl U, Wickrema A
Semin Hematol
. 2021 Jan;
58(1):15-26.
PMID: 33509439
Erythroid differentiation program is comprised of lineage commitment, erythroid progenitor proliferation, and termination differentiation. Each stage of the differentiation program is heavily influenced by epigenetic modifiers that alter the epigenome...
6.
Sundaravel S, Steidl U
J Exp Med
. 2021 Jan;
218(2).
PMID: 33427877
In this issue of JEM, Louka et al. (https://doi.org/10.1084/jem.20180853) report that leukemia stem cells lie within the phenotypic hematopoietic stem cell and progenitor cell compartments in juvenile myelomonocytic leukemia (JMML)....
7.
Sundaravel S, Kuo W, Jeong J, Choudhary G, Gordon-Mitchell S, Liu H, et al.
Clin Cancer Res
. 2019 Jul;
25(18):5638-5649.
PMID: 31308061
Purpose: Myelodysplastic syndromes (MDS) with deletion of chromosome 7q/7 [-7/(del)7q MDS] is associated with worse outcomes and needs novel insights into pathogenesis. Reduced expression of signaling protein dedicator of cytokinesis...
8.
Jeong J, Gu X, Nie J, Sundaravel S, Liu H, Kuo W, et al.
Cancer Discov
. 2019 Apr;
9(6):778-795.
PMID: 30944118
Even though the Ten-eleven translocation (TET) enzymes catalyze the generation of 5-hydroxymethylcytosines required for lineage commitment and subsequent differentiation of stem cells into erythroid cells, the mechanisms that link extracellular...
9.
Gilles L, Arslan A, Marinaccio C, Wen Q, Arya P, McNulty M, et al.
J Clin Invest
. 2017 Feb;
127(4):1316-1320.
PMID: 28240607
Primary myelofibrosis (PMF) is a clonal hematologic malignancy characterized by BM fibrosis, extramedullary hematopoiesis, circulating CD34+ cells, splenomegaly, and a propensity to evolve to acute myeloid leukemia. Moreover, the spleen...
10.
Sundaravel S, Duggan R, Bhagat T, Ebenezer D, Liu H, Yu Y, et al.
Proc Natl Acad Sci U S A
. 2015 Nov;
112(46):E6359-68.
PMID: 26578796
Anemia is the predominant clinical manifestation of myelodysplastic syndromes (MDS). Loss or deletion of chromosome 7 is commonly seen in MDS and leads to a poor prognosis. However, the identity...