Srilakshmi Srinivasan
Overview
Explore the profile of Srilakshmi Srinivasan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
28
Citations
659
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Subramaniam S, Jeet V, Gunter J, Janjua Khan T, Feng Y, Clements J, et al.
Cancer Lett
. 2025 Feb;
616:217522.
PMID: 39924080
Pyruvate Dehydrogenase Kinase 1 (PDK1) regulates glycolysis and oxidative phosphorylation pathways and is linked to prostate cancer metastasis and poor prognosis. The therapeutic application of 2,2-dichloroacetophenone (DAP), a PDK1 inhibitor,...
2.
Kooshan Z, Srinivasan S, Janjua T, Popat A, Batra J
Eur J Pharmacol
. 2025 Jan;
991:177300.
PMID: 39870236
Pyruvate dehydrogenase kinase-1 (PDK1) plays a crucial role in cancer cell metabolism by regulating the glycolytic pathway. Although, inhibitors targeting PDK1 have been effective in inhibiting glycolysis in multiple cancers,...
3.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Janaththani P, et al.
Nat Commun
. 2024 Nov;
15(1):9587.
PMID: 39505858
Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA)...
4.
Fernando A, Liyanage C, Srinivasan S, Panchadsaram J, Rothnagel J, Clements J, et al.
Commun Med (Lond)
. 2024 Nov;
4(1):224.
PMID: 39487222
Background: Prostate cancer (PCa) is a commonly diagnosed cancer. Genome-wide association studies have implicated Iroquois homeobox 4 (IRX4) in PCa susceptibility, yet its functional roles remain unclear. We discovered a...
5.
Janaththani P, Tevz G, Fernando A, Malik A, Rockstroh A, Kryza T, et al.
Res Sq
. 2023 Dec;
PMID: 38076926
Genome-wide association studies have linked Iroquois-Homeobox 4 (IRX4) as a robust expression quantitative-trait locus associated with prostate cancer (PCa) risk. However, the intricate mechanism and regulatory factors governing IRX4 expression...
6.
Moya L, Walpole C, Rae F, Srinivasan S, Seim I, Lai J, et al.
Prostate Cancer Prostatic Dis
. 2023 Jun;
26(3):614-624.
PMID: 37264224
Background: Prostate cancer is a broad-spectrum disease, spanning from indolent to a highly aggressive lethal malignancy. Prostate cancer cell lines are essential tools to understanding the basic features of this...
7.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Panchadsaram J, et al.
Res Sq
. 2023 Apr;
PMID: 37034758
Genetic variation at the 19q13.3 locus is linked with prostate cancer susceptibility. The non-synonymous SNP, rs17632542 (c.536T>C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional...
8.
Srinivasan S, Kryza T, Batra J, Clements J
Nat Rev Cancer
. 2022 Feb;
22(4):223-238.
PMID: 35102281
Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment. KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including hormones and growth factors, membrane receptors and the extracellular...
9.
Lin H, Huang P, Cheng C, Tung H, Fang Z, Berglund A, et al.
Sci Rep
. 2021 Apr;
11(1):9264.
PMID: 33927218
Risk classification for prostate cancer (PCa) aggressiveness and underlying mechanisms remain inadequate. Interactions between single nucleotide polymorphisms (SNPs) may provide a solution to fill these gaps. To identify SNP-SNP interactions...
10.
Chandra S, Srinivasan S, Batra J
Cancer Med
. 2021 Feb;
10(5):1791-1804.
PMID: 33580750
Hepatocyte nuclear factor 1 beta (HNF1 β/B) exists as a homeobox transcription factor having a vital role in the embryonic development of organs mainly liver, kidney and pancreas. Initially described...