Sonke Cordeiro
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Explore the profile of Sonke Cordeiro including associated specialties, affiliations and a list of published articles.
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10
Citations
230
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Recent Articles
1.
Rodstrom K, Eymsh B, Proks P, Hayre M, Cordeiro S, Mendez-Otalvaro E, et al.
Nat Struct Mol Biol
. 2025 Feb;
PMID: 40011745
THIK-1 (KCNK13) is a halothane-inhibited and anionic-lipid-activated two-pore domain (K2P) K channel implicated in microglial activation and neuroinflammation, and a current target for the treatment of neurodegenerative disorders, for example...
2.
Neelsen L, Riel E, Rinne S, Schmid F, Jurs B, Bedoya M, et al.
Nat Commun
. 2024 Aug;
15(1):7545.
PMID: 39215031
Two-pore domain K (K) channel activity was previously thought to be controlled primarily via a selectivity filter (SF) gate. However, recent crystal structures of TASK-1 and TASK-2 revealed a lower...
3.
Bauer I, Rimbach G, Cordeiro S, Bosy-Westphal A, Weghuber J, Ipharraguerre I, et al.
Front Pharmacol
. 2024 Jul;
15:1396292.
PMID: 38989154
Plant extracts are increasingly recognized for their potential in modulating (postprandial) blood glucose levels. In this context, root extracts are of particular interest due to their high concentrations and often...
4.
Riel E, Jurs B, Cordeiro S, Musinszki M, Schewe M, Baukrowitz T
J Gen Physiol
. 2021 Dec;
154(2).
PMID: 34928298
Work over the past three decades has greatly advanced our understanding of the regulation of Kir K+ channels by polyanionic lipids of the phosphoinositide (e.g., PIP2) and fatty acid metabolism...
5.
Cordeiro S, Finol-Urdaneta R, Kopfer D, Markushina A, Song J, French R, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
116(3):1059-1064.
PMID: 30593566
The vast complexity of native heteromeric K channels is largely unexplored. Defining the composition and subunit arrangement of individual subunits in native heteromeric K channels and establishing their physiological roles...
6.
Schewe M, Nematian-Ardestani E, Sun H, Musinszki M, Cordeiro S, Bucci G, et al.
Cell
. 2016 Feb;
164(5):937-49.
PMID: 26919430
Two-pore domain (K2P) K(+) channels are major regulators of excitability that endow cells with an outwardly rectifying background "leak" conductance. In some K2P channels, strong voltage-dependent activation has been observed,...
7.
Schneider N, Cordeiro S, Machtens J, Braams S, Rauen T, Fahlke C
J Biol Chem
. 2013 Dec;
289(3):1815-24.
PMID: 24307171
In the mammalian retina, glutamate uptake is mediated by members of a family of glutamate transporters known as "excitatory amino acid transporters (EAATs)." Here we cloned and functionally characterized two...
8.
Cordeiro S, Guseva D, Wulfsen I, Bauer C
PLoS One
. 2011 Dec;
6(12):e29490.
PMID: 22206018
In response to light, most retinal neurons exhibit gradual changes in membrane potential. Therefore K+ channels that mediate threshold currents are well-suited for the fine-tuning of signal transduction. In the...
9.
Reichhart N, Milenkovic V, Halsband C, Cordeiro S, Strauss O
Exp Eye Res
. 2010 Aug;
91(5):630-9.
PMID: 20696156
Best's vitelliforme macular degeneration is an inherited retinal degeneration associated with a reduction of the light-peak in the patient's electro-oculogram. Bestrophin-1, the product of the disease-promoting/forming gene can function as...
10.
Cordeiro S, Strauss O
Graefes Arch Clin Exp Ophthalmol
. 2010 Jul;
249(1):47-54.
PMID: 20607548
Background: The retinal pigment epithelium (RPE) fulfills a large variety of tasks that are important for visual function. Many of these tasks, such as phagocytosis, growth factor secretion, or transepithelial...