Simone Picelli
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Explore the profile of Simone Picelli including associated specialties, affiliations and a list of published articles.
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37
Citations
6683
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Recent Articles
11.
Dobie R, Wilson-Kanamori J, Henderson B, Smith J, Matchett K, Portman J, et al.
Cell Rep
. 2019 Nov;
29(7):1832-1847.e8.
PMID: 31722201
Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are...
12.
Picelli S
Methods Mol Biol
. 2019 Apr;
1979:25-44.
PMID: 31028630
In the last few years single-cell RNA sequencing (scRNA-seq) has enabled the investigation of cellular heterogeneity at the transcriptional level, the characterization of rare cell types as well as the...
13.
Lafzi A, Moutinho C, Picelli S, Heyn H
Nat Protoc
. 2018 Nov;
13(12):2742-2757.
PMID: 30446749
Single-cell RNA sequencing is at the forefront of high-resolution phenotyping experiments for complex samples. Although this methodology requires specialized equipment and expertise, it is now widely applied in research. However,...
14.
Thutkawkorapin J, Mahdessian H, Barber T, Picelli S, von Holst S, Lundin J, et al.
Oncotarget
. 2018 Mar;
9(13):11170-11179.
PMID: 29541405
Highly penetrant cancer syndromes account for less than 5% of all cases with familial colorectal cancer (CRC), and other genetic contribution explains the majority of the genetic contribution to CRC....
15.
Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S, Adamovic T, et al.
Oncotarget
. 2017 Dec;
8(61):102769-102782.
PMID: 29262523
Most non- breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on chromosome...
16.
Hochgerner H, Lonnerberg P, Hodge R, Mikes J, Heskol A, Hubschle H, et al.
Sci Rep
. 2017 Nov;
7(1):16327.
PMID: 29180631
Single-cell RNA-seq has become routine for discovering cell types and revealing cellular diversity, but archived human brain samples still pose a challenge to current high-throughput platforms. We present STRT-seq-2i, an...
17.
Forsberg A, Keranen A, von Holst S, Picelli S, Papadogiannakis N, Ghazi S, et al.
Anticancer Res
. 2017 Apr;
37(4):1831-1835.
PMID: 28373448
Background/aim: Most known cancer syndromes confer an increased risk of more than one tumour types, and families with more than one colorectal cancer often segregate other cancers as well. The...
18.
Segerstolpe A, Palasantza A, Eliasson P, Andersson E, Andreasson A, Sun X, et al.
Cell Metab
. 2016 Sep;
24(4):593-607.
PMID: 27667667
Hormone-secreting cells within pancreatic islets of Langerhans play important roles in metabolic homeostasis and disease. However, their transcriptional characterization is still incomplete. Here, we sequenced the transcriptomes of thousands of...
19.
Picelli S
RNA Biol
. 2016 Jul;
14(5):637-650.
PMID: 27442339
Genome-wide single-cell analysis represents the ultimate frontier of genomics research. In particular, single-cell RNA-sequencing (scRNA-seq) studies have been boosted in the last few years by an explosion of new technologies...
20.
Bjorklund A, Forkel M, Picelli S, Konya V, Theorell J, Friberg D, et al.
Nat Immunol
. 2016 Feb;
17(4):451-60.
PMID: 26878113
Innate lymphoid cells (ILCs) are increasingly appreciated as important participants in homeostasis and inflammation. Substantial plasticity and heterogeneity among ILC populations have been reported. Here we have delineated the heterogeneity...