Susanna von Holst
Overview
Explore the profile of Susanna von Holst including associated specialties, affiliations and a list of published articles.
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10
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501
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Recent Articles
1.
Wallander K, Liu W, von Holst S, Thutkawkorapin J, Kontham V, Forsberg A, et al.
Genes Chromosomes Cancer
. 2019 Jul;
58(11):775-782.
PMID: 31334572
Colorectal cancer (CRC), prostate cancer (PrC), and gastric cancer (GC) are common worldwide, and the incidence is to a certain extent dependent on genetics. We have recently shown that in...
2.
von Holst S, Jiao X, Liu W, Kontham V, Thutkawkorapin J, Ringdahl J, et al.
Eur J Hum Genet
. 2019 Apr;
27(8):1286-1295.
PMID: 30952955
Colorectal cancer (CRC) is one of the major cancer types in the western world including Sweden. However, known genetic risk factors could only explain a limited part of heritability of...
3.
Thutkawkorapin J, Mahdessian H, Barber T, Picelli S, von Holst S, Lundin J, et al.
Oncotarget
. 2018 Mar;
9(13):11170-11179.
PMID: 29541405
Highly penetrant cancer syndromes account for less than 5% of all cases with familial colorectal cancer (CRC), and other genetic contribution explains the majority of the genetic contribution to CRC....
4.
Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S, Adamovic T, et al.
Oncotarget
. 2017 Dec;
8(61):102769-102782.
PMID: 29262523
Most non- breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on chromosome...
5.
Forsberg A, Keranen A, von Holst S, Picelli S, Papadogiannakis N, Ghazi S, et al.
Anticancer Res
. 2017 Apr;
37(4):1831-1835.
PMID: 28373448
Background/aim: Most known cancer syndromes confer an increased risk of more than one tumour types, and families with more than one colorectal cancer often segregate other cancers as well. The...
6.
Kontham V, von Holst S, Lindblom A
PLoS One
. 2013 Dec;
8(12):e83936.
PMID: 24349560
Family history is a major risk factor for colorectal cancer and many families segregate the disease as a seemingly monogenic trait. A minority of familial colorectal cancer could be explained...
7.
Dunlop M, Tenesa A, Farrington S, Ballereau S, Brewster D, Koessler T, et al.
Gut
. 2012 Apr;
62(6):871-81.
PMID: 22490517
Objective: Colorectal cancer (CRC) has a substantial heritable component. Common genetic variation has been shown to contribute to CRC risk. A study was conducted in a large multi-population study to...
8.
Ghazi S, von Holst S, Picelli S, Lindforss U, Tenesa A, Farrington S, et al.
Am J Pathol
. 2010 Dec;
177(6):2688-93.
PMID: 21119214
Recent genome-wide association studies have identified multiple genetic loci and single nucleotide polymorphisms (SNPs) associated with either increased or decreased risk of colorectal cancer (CRC). In the present study, our...
9.
Picelli S, von Holst S, Wessendorf P
Cancer Genomics Proteomics
. 2010 Jan;
6(6):305-16.
PMID: 20065317
High-penetrance mutations in a small group of genes have been identified as the causal agent of colorectal cancer (CRC) in high-risk families. Our understanding of the sporadic cases is, however,...
10.
Stacey S, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson S, et al.
Nat Genet
. 2007 May;
39(7):865-9.
PMID: 17529974
Familial clustering studies indicate that breast cancer risk has a substantial genetic component. To identify new breast cancer risk variants, we genotyped approximately 300,000 SNPs in 1,600 Icelandic individuals with...