Rickard Sandberg
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Explore the profile of Rickard Sandberg including associated specialties, affiliations and a list of published articles.
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106
Citations
17221
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Recent Articles
1.
Cougnoux A, Mahmoud L, Johnsson P, Eroglu A, Gsell L, Rosenbauer J, et al.
Sci Rep
. 2025 Jan;
15(1):3811.
PMID: 39885179
Combining 3D cultures such as tumor spheroids and organoids with spatial omics holds great potential for tissue biology and cancer research. Yet, this potential is presently limited by technical and...
2.
Grommisch D, Lund H, Eenjes E, Julien A, Goritz C, Harris R, et al.
Dev Cell
. 2024 Oct;
60(2):320-336.e9.
PMID: 39426382
Regionalized disease prevalence is a common feature of the gastrointestinal tract. Herein, we employed regionally resolved Smart-seq3 single-cell sequencing, generating a comprehensive cell atlas of the adult mouse esophagus. Characterizing...
3.
Noble J, Lentini A, Hagemann-Jensen M, Sandberg R, Reinius B
Nat Commun
. 2024 Sep;
15(1):8373.
PMID: 39333520
Single-cell RNA-sequencing (scRNAseq) is revolutionizing biomedicine, propelled by advances in methodology, ease of use, and cost reduction of library preparation. Over the past decade, there have been remarkable technical improvements...
4.
Ramskold D, Hendriks G, Larsson A, Mayr J, Ziegenhain C, Hagemann-Jensen M, et al.
Nat Cell Biol
. 2024 Aug;
26(10):1725-1733.
PMID: 39198695
Analyses of transcriptional bursting from single-cell RNA-sequencing data have revealed patterns of variation and regulation in the kinetic parameters that could be inferred. Here we profiled newly transcribed (4-thiouridine-labelled) RNA...
5.
Demirci I, Larsson A, Chen X, Hartman J, Sandberg R, Frisen J
Genome Biol
. 2024 Aug;
25(1):214.
PMID: 39123248
Analysis of clonal dynamics in human tissues is enabled by somatic genetic variation. Here, we show that analysis of mitochondrial mutations in single cells is dramatically improved in females when...
6.
Carrelha J, Mazzi S, Winroth A, Hagemann-Jensen M, Ziegenhain C, Hogstrand K, et al.
Nat Immunol
. 2024 May;
25(6):1007-1019.
PMID: 38816617
Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of increasingly lineage-restricted progenitors. Although insults to the blood-forming system highlight...
7.
Di Martino E, Ambikan A, Ramskold D, Umekawa T, Giatrellis S, Vacondio D, et al.
iScience
. 2024 Mar;
27(4):109346.
PMID: 38500830
Neonatal hypoxia-ischemia (HI) is a major cause of perinatal death and long-term disabilities worldwide. Post-ischemic neuroinflammation plays a pivotal role in HI pathophysiology. In the present study, we investigated the...
8.
Mold J, Weissman M, Ratz M, Hagemann-Jensen M, Hard J, Eriksson C, et al.
Cell Syst
. 2024 Feb;
15(2):149-165.e10.
PMID: 38340731
Cell types can be classified according to shared patterns of transcription. Non-genetic variability among individual cells of the same type has been ascribed to stochastic transcriptional bursting and transient cell...
9.
Hunt G, Vaid R, Pirogov S, Pfab A, Ziegenhain C, Sandberg R, et al.
Genome Biol
. 2024 Jan;
25(1):2.
PMID: 38166964
Background: Formation of tissue-specific transcriptional programs underlies multicellular development, including dorsoventral (DV) patterning of the Drosophila embryo. This involves interactions between transcriptional enhancers and promoters in a chromatin context, but...
10.
Nikopoulou C, Kleinenkuhnen N, Parekh S, Sandoval T, Ziegenhain C, Schneider F, et al.
Nat Aging
. 2023 Nov;
3(11):1430-1445.
PMID: 37946043
Tissues within an organism and even cell types within a tissue can age with different velocities. However, it is unclear whether cells of one type experience different aging trajectories within...