Simon Junankar
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Explore the profile of Simon Junankar including associated specialties, affiliations and a list of published articles.
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19
Citations
1801
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Recent Articles
1.
An F, Ge Y, Ye W, Ji L, Chen K, Wang Y, et al.
Cancer Biomark
. 2024 Sep;
41(1):25-40.
PMID: 39269824
Background: Chronic atrophy gastritis (CAG) is a high-risk pre-cancerous lesion for gastric cancer (GC). The early and accurate detection and discrimination of CAG from benign forms of gastritis (e.g. chronic...
2.
Filipe E, Velayuthar S, Philp A, Nobis M, Latham S, Parker A, et al.
Adv Sci (Weinh)
. 2024 Apr;
11(23):e2307963.
PMID: 38602451
In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter...
3.
Baldwin L, Bartonicek N, Yang J, Wu S, Deng N, Roden D, et al.
Nat Commun
. 2022 Nov;
13(1):6539.
PMID: 36344500
Cancers evade the immune system through the process of cancer immunoediting. While immune checkpoint inhibitors are effective for reactivating tumour immunity in some cancer types, many other solid cancers, including...
4.
Wu S, Al-Eryani G, Roden D, Junankar S, Harvey K, Andersson A, et al.
Nat Genet
. 2021 Sep;
53(9):1334-1347.
PMID: 34493872
Breast cancers are complex cellular ecosystems where heterotypic interactions play central roles in disease progression and response to therapy. However, our knowledge of their cellular composition and organization is limited....
5.
Wu S, Roden D, Al-Eryani G, Bartonicek N, Harvey K, Cazet A, et al.
Genome Med
. 2021 May;
13(1):81.
PMID: 33971952
Background: High throughput single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for exploring cellular heterogeneity among complex human cancers. scRNA-Seq studies using fresh human surgical tissue are logistically...
6.
Holliday H, Roden D, Junankar S, Wu S, Baker L, Krisp C, et al.
iScience
. 2021 Feb;
24(2):102072.
PMID: 33554073
Inhibitor of differentiation (ID) proteins dimerize with basic HLH (bHLH) transcription factors, repressing transcription of lineage-specification genes across diverse cellular lineages. ID4 is a key regulator of mammary stem cells;...
7.
Wu S, Roden D, Wang C, Holliday H, Harvey K, Cazet A, et al.
EMBO J
. 2020 Aug;
39(19):e104063.
PMID: 32790115
The tumour stroma regulates nearly all stages of carcinogenesis. Stromal heterogeneity in human triple-negative breast cancers (TNBCs) remains poorly understood, limiting the development of stromal-targeted therapies. Single-cell RNA sequencing of...
8.
Teo W, Holliday H, Karthikeyan N, Cazet A, Roden D, Harvey K, et al.
Front Cell Dev Biol
. 2020 Aug;
8:552.
PMID: 32766238
Breast cancers display phenotypic and functional heterogeneity and several lines of evidence support the existence of cancer stem cells (CSCs) in certain breast cancers, a minor population of cells capable...
9.
Baker L, Holliday H, Roden D, Krisp C, Wu S, Junankar S, et al.
Breast Cancer Res
. 2020 Jun;
22(1):63.
PMID: 32527287
Background: Basal-like breast cancer (BLBC) is a poorly characterised, heterogeneous disease. Patients are diagnosed with aggressive, high-grade tumours and often relapse with chemotherapy resistance. Detailed understanding of the molecular underpinnings...
10.
Singh M, Al-Eryani G, Carswell S, Ferguson J, Blackburn J, Barton K, et al.
Nat Commun
. 2019 Jul;
10(1):3120.
PMID: 31311926
High-throughput single-cell RNA sequencing is a powerful technique but only generates short reads from one end of a cDNA template, limiting the reconstruction of highly diverse sequences such as antigen...