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Siddhartha Mukherjee

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Articles 79
Citations 4105
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Recent Articles
11.
Borot F, Humbert O, Newby G, Fields E, Kohli S, Radtke S, et al.
bioRxiv . 2023 Mar; PMID: 36865281
Graphical Abstract:
12.
Lyu M, Huang M, Zeng K, Li L, Khoury J, Nishimoto M, et al.
Cytotherapy . 2022 Nov; 25(3):245-253. PMID: 36437190
Background Aims: CD4CD25CD127 regulatory T cells (Tregs) are responsible for maintaining immune homeostasis. Tregs can be rendered defective and deficient as a result of the immune imbalance seen in lung...
13.
Burke A, Borot F, Du X, Churchill M, Ding J, Grass A, et al.
Oncogene . 2022 Nov; 42(1):26-34. PMID: 36357573
Many therapeutic bispecific T-cell engagers (BiTEs) are in clinical trials. A modular and efficient process to create BiTEs would accelerate their development and clinical applicability. In this study, we present...
14.
Alqahtani M, Du X, Bhattacharyya S, Alawadi A, Al Mahmeed H, Al Sayed J, et al.
Sci Rep . 2022 Jun; 12(1):9236. PMID: 35654940
With the emergence of new SARS-Cov2 variants, critical questions have arisen about: (1) the effectiveness of the available COVID-19 vaccines developed to protect against the original Wuhan (wild type) variant...
15.
Galan-Diez M, Borot F, Ali A, Zhao J, Gil-Iturbe E, Shan X, et al.
Cancer Discov . 2022 Jan; 12(4):1106-1127. PMID: 35046097
Significance: AML remains recalcitrant to treatments due to the emergence of resistant clones. We show a leukemia-cell nonautonomous progression mechanism that involves activation of a kynurenine-HTR1B-SAA-IDO1 axis between AML cells...
16.
Lieu Y, Liu Z, Ali A, Wei X, Penson A, Zhang J, et al.
Proc Natl Acad Sci U S A . 2021 Dec; 119(1). PMID: 34930825
SF3B1 is the most frequently mutated RNA splicing factor in cancer, including in ∼25% of myelodysplastic syndromes (MDS) patients. SF3B1-mutated MDS, which is strongly associated with ringed sideroblast morphology, is...
17.
Kobayashi H, Gieniec K, Lannagan T, Wang T, Asai N, Mizutani Y, et al.
Gastroenterology . 2021 Dec; 162(3):890-906. PMID: 34883119
Background & Aims: Cancer-associated fibroblasts (CAFs) play an important role in colorectal cancer (CRC) progression and predict poor prognosis in CRC patients. However, the cellular origins of CAFs remain unknown,...
18.
Mandal J, Mukherjee S, Saha N, Halder N, Biswas T, Chakraborty S, et al.
Molecules . 2021 Nov; 26(22). PMID: 34834110
In-situ rehabilitation of fly ash at dumping sites has rarely been addressed for crop production due to growth-related constraints, largely of heavy metal (HM) contamination in soils and crops. Current...
19.
Mukherjee S, Singh R, James M, Ray S
Phys Rev Lett . 2021 Sep; 127(11):118001. PMID: 34558935
Bacterial swarms display intriguing dynamical states like active turbulence. Now, using a hydrodynamic model, we show that such dense active suspensions manifest superdiffusion, via Lévy walks, which masquerades as a...
20.
Mukherjee S, Elia A, Calcinotto A
Swiss Med Wkly . 2021 Apr; 151:w20483. PMID: 33872378
Tumour-infiltrating myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid cells. The main feature of MDSCs is their ability to suppress T-cell activation and function, which leads to immunosuppressive...