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Shuyu Ren

Explore the profile of Shuyu Ren including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1496
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Recent Articles
1.
Ren S, Pan F, Jin J
Front Neurol . 2024 Apr; 15:1371298. PMID: 38628699
Background: Alzheimer's disease (AD) is the most prevalent type of dementia and represents 60-80% of dementia cases. AD affects over 32 million people globally, and 8.1% of affected females and...
2.
Zhang Y, Du Y, Ren S, Li Y, Zhang X, Cao X, et al.
Ann Pharmacother . 2023 Sep; 58(6):605-613. PMID: 37702380
Background: The effect of drug-drug interaction (DDI) between tacrolimus and voriconazole on the pharmacokinetics of tacrolimus in different genotypes has not been reported in previous studies. Objective: The objective of...
3.
Li Y, Yang Z, Ren S, Shen B, Zhang Y, Zong H, et al.
Gene . 2023 Jun; 878:147589. PMID: 37364698
Objective: To evaluate the relationship between GLP-1R gene polymorphisms and type 2 diabetes mellitus with dyslipidemia and without dyslipidemia in China. Methods: A total of 200 patients with Type 2...
4.
Sun L, Lin P, Chen Y, Yu H, Ren S, Wang J, et al.
Theranostics . 2020 May; 10(12):5581-5599. PMID: 32373233
There is a continued need for investigating the roles of microRNAs and their targets on the pathogenesis of pulmonary arterial hypertension (PAH) vascular remodeling. We recently identified the association of...
5.
Chen G, Chen H, Ren S, Xia M, Zhu J, Liu Y, et al.
Kidney Int . 2019 May; 96(2):409-420. PMID: 31101365
DNA methylation has been implicated in the pathogenesis of diabetic kidney disease (DKD), but the underlying mechanisms remain unclear. In this study, we tested the hypothesis that aberrant DNA methylation...
6.
Dang L, Aburatani T, Marsh G, Johnson B, Alimperti S, Yoon C, et al.
Biomaterials . 2017 Jul; 141:314-329. PMID: 28711779
Loss of the microvascular (MV) network results in tissue ischemia, loss of tissue function, and is a hallmark of chronic diseases. The incorporation of a functional vascular network with that...
7.
Johnson B, Ren S, Karaca G, Gomez I, Fligny C, Smith B, et al.
J Am Soc Nephrol . 2017 Jan; 28(6):1769-1782. PMID: 28130402
Connective tissue growth factor (CTGF), a matrix-associated protein with four distinct cytokine binding domains, has roles in vasculogenesis, wound healing responses, and fibrogenesis and is upregulated in fibroblasts and myofibroblasts...
8.
Ligresti G, Nagao R, Xue J, Choi Y, Xu J, Ren S, et al.
J Am Soc Nephrol . 2015 Dec; 27(8):2370-81. PMID: 26657868
Human kidney peritubular capillaries are particularly susceptible to injury, resulting in dysregulated angiogenesis, capillary rarefaction and regression, and progressive loss of kidney function. However, little is known about the structure...
9.
Nakagawa N, Xin C, Roach A, Naiman N, Shankland S, Ligresti G, et al.
Kidney Int . 2015 Feb; 87(6):1125-40. PMID: 25651362
MicroRNAs, activated by the enzyme Dicer1, control post-transcriptional gene expression. Dicer1 has important roles in the epithelium during nephrogenesis, but its function in stromal cells during kidney development is unknown....
10.
Gomez I, Mackenna D, Johnson B, Kaimal V, Roach A, Ren S, et al.
J Clin Invest . 2014 Nov; 125(1):141-56. PMID: 25415439
MicroRNA-21 (miR-21) contributes to the pathogenesis of fibrogenic diseases in multiple organs, including the kidneys, potentially by silencing metabolic pathways that are critical for cellular ATP generation, ROS production, and...