Josef Pfeilschifter
Overview
Explore the profile of Josef Pfeilschifter including associated specialties, affiliations and a list of published articles.
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312
Citations
6643
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Recent Articles
1.
Tondello C, Bender C, Golden G, Puppe D, Blickberndt E, Bayer M, et al.
JCI Insight
. 2025 Feb;
PMID: 40014407
Type 1 diabetes (T1D) is precipitated by the autoimmune destruction of the insulin-producing β-cells in the pancreatic islets of Langerhans. Chemokines have been identified as major conductors of islet infiltration...
2.
Eberhardt W, Nasrullah U, Pfeilschifter J
Cells
. 2025 Jan;
14(2).
PMID: 39851496
Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis....
3.
Buitkamp S, Schwalm S, Jakobi K, Ferreiros N, Wunsche C, Zeuzem S, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596241
Sphingolipids play a major role in the regulation of hepatocellular apoptosis and proliferation. We have previously identified sphingolipid metabolites as biomarkers of chronic liver disease and hepatocellular carcinoma. Human hepatocellular...
4.
Gulbins E, Pfeilschifter J
Pflugers Arch
. 2024 Nov;
476(12):1777-1778.
PMID: 39527143
No abstract available.
5.
Volk L, Bruun J, Trautmann S, Thomas D, Schwalm S, Pfeilschifter J, et al.
Pflugers Arch
. 2024 Oct;
476(12):1895-1911.
PMID: 39392480
Sphingosine-1-phosphate (S1P) is a ubiquitous lipid mediator, acting via specific G-protein-coupled receptors (GPCR) and intracellularly. Previous work has shown that deletion of S1P lyase caused a chronic elevation of cytosolic...
6.
Schwalm S, Manaila R, Oftring A, Schaefer L, von Gunten S, Pfeilschifter J
Pflugers Arch
. 2024 Oct;
476(12):1845-1861.
PMID: 39384640
Chronic kidney disease (CKD) is a multifactorial condition with diverse etiologies, such as diabetes mellitus, hypertension, and genetic disorders, often culminating in end-stage renal disease (ESRD). A hallmark of CKD...
7.
Doiron J, Elbatreek M, Xia H, Yu X, Gehred N, Gromova T, et al.
bioRxiv
. 2024 Sep;
PMID: 39345440
Background: Heart failure with preserved ejection fraction (HFpEF) is a significant public health concern with limited treatment options. Dysregulated nitric oxide-mediated signaling has been implicated in HFpEF pathophysiology, however, little...
8.
Amin M, Ali S, Engelhardt K, Nasrullah U, Preis E, Schaefer J, et al.
Eur J Pharm Biopharm
. 2024 Sep;
204:114503.
PMID: 39303950
Since the available treatments are not highly effective to combat cancer, therefore, the alternative strategies are unavoidable. Photodynamic therapy (PDT) is one of the emerging approaches which is target specific...
9.
Glueck M, Lucaciu A, Subburayalu J, Kestner R, Pfeilschifter W, Vutukuri R, et al.
Pflugers Arch
. 2024 Sep;
476(12):1833-1843.
PMID: 39297971
Sphingosine-1-phosphate (S1P) is a bioactive lipid signaling molecule with pleiotropic implications by both auto- and paracrine signaling. Signaling occurs by engaging five G protein-coupled receptors (S1P) or intracellular pathways. While...
10.
Pfeilschifter J, Gulbins E
Pflugers Arch
. 2024 Apr;
476(12):1779-1780.
PMID: 38592461
No abstract available.