Andrea Huwiler
Overview
Explore the profile of Andrea Huwiler including associated specialties, affiliations and a list of published articles.
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114
Citations
2120
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Recent Articles
1.
Prell A, Wigger D, Huwiler A, Schumacher F, Kleuser B
J Lipid Res
. 2024 Aug;
65(10):100631.
PMID: 39182604
Sphingosine kinases (SphKs), enzymes that produce the bioactive lipids dihydrosphingosine 1-phosphate (dhS1P) and sphingosine 1-phosphate (S1P), are associated with various diseases, including cancer and infections. For this reason, a number...
2.
Manaila R, Huwiler A
Inn Med (Heidelb)
. 2023 Dec;
65(1):22-28.
PMID: 38110759
The prevalence for chronic kidney disease (CKD) has steadily increased over the past decades. It is a gradually progressive disease that is associated with several comorbidities including cardiovascular diseases, hypertension,...
3.
Huwiler A
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298478
The last two decades have boosted research on sphingolipids as bioactive and signaling molecules [...].
4.
Huwiler A, Beck K, Pfeilschifter J
Metabolites
. 2023 Mar;
13(3).
PMID: 36984866
Redox-active mediators are now appreciated as powerful molecules to regulate cellular dynamics such as viability, proliferation, migration, cell contraction, and relaxation, as well as gene expression under physiological and pathophysiological...
5.
Imeri F, Stepanovska Tanturovska B, Manaila R, Pavenstadt H, Pfeilschifter J, Huwiler A
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36834691
Sphingosine 1-phosphate (S1P) lyase (SPL, ) is an ER-associated enzyme that irreversibly degrades the bioactive lipid, S1P, and thereby regulates multiple cellular functions attributed to S1P. Biallelic mutations in the...
6.
Stepanovska Tanturovska B, Manaila R, Fabbro D, Huwiler A
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36834678
Kidney cancer is among the top ten most common cancers to date. Within the kidney, renal cell carcinoma (RCC) is the most common solid lesion occurring. While various risk factors...
7.
Beyoglu D, Schwalm S, Semmo N, Huwiler A, Idle J
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674922
A mass spectrometry-based lipidomic investigation of 30 patients with chronic hepatitis C virus (HCV) infection and 30 age- and sex-matched healthy blood donor controls was undertaken. The clustering and complete...
8.
Hafizi R, Imeri F, Stepanovska Tanturovska B, Manaila R, Schwalm S, Trautmann S, et al.
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35682566
Erythropoietin (Epo) is a crucial hormone regulating red blood cell number and consequently the hematocrit. Epo is mainly produced in the kidney by interstitial fibroblast-like cells. Previously, we have shown...
9.
Theodoropoulou M, Psarra A, Erhardt M, Nikolaou A, Gerogiannopoulou A, Hadjipavlou-Litina D, et al.
Biomolecules
. 2022 Feb;
12(2).
PMID: 35204768
The quest for novel agents to regulate the generation of prostaglandin E (PGE) is of high importance because this eicosanoid is a key player in inflammatory diseases. We synthesized a...
10.
Hafizi R, Imeri F, Wenger R, Huwiler A
Int J Mol Sci
. 2021 Sep;
22(17).
PMID: 34502385
Erythropoietin (Epo) is the critical hormone for erythropoiesis. In adults, Epo is mainly produced by a subset of interstitial fibroblasts in the kidney, with minor amounts being produced in the...