Sherri Osborne-Lawrence
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Explore the profile of Sherri Osborne-Lawrence including associated specialties, affiliations and a list of published articles.
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45
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1731
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Recent Articles
1.
Varshney S, Shankar K, Kerr H, Anderson L, Gupta D, Metzger N, et al.
Endocrinology
. 2024 Sep;
165(11).
PMID: 39331742
The hormone ghrelin serves a protective role in cancer-related anorexia-cachexia syndrome (CACS)-a condition in which plasma levels of ghrelin rise, its administration lessens CACS severity, and experimentally reduced signaling by...
2.
Stark R, Dempsey H, Kleeman E, Sassi M, Osborne-Lawrence S, Sheybani-Deloui S, et al.
Mol Metab
. 2024 Sep;
89:102025.
PMID: 39236785
Objective: Although the metabolic state of an organism affects olfactory function, the precise mechanisms and their impact on behavior and metabolism remain unknown. Here, we assess whether ghrelin receptors (GHSRs)...
3.
Gupta D, Burstein A, Schwalbe D, Shankar K, Varshney S, Singh O, et al.
J Clin Invest
. 2024 May;
134(10).
PMID: 38747294
No abstract available.
4.
Shankar K, Metzger N, Lawrence C, Gupta D, Osborne-Lawrence S, Varshney S, et al.
Mol Metab
. 2024 May;
84:101950.
PMID: 38697291
Objective: The number of individuals affected by metabolic dysfunction associated fatty liver disease [1] is on the rise, yet hormonal contributors to the condition remain incompletely described and only a...
5.
Gupta D, Burstein A, Shankar K, Varshney S, Singh O, Osborne-Lawrence S, et al.
Endocrinology
. 2024 Apr;
165(6).
PMID: 38626085
Reducing ghrelin by ghrelin gene knockout (GKO), ghrelin-cell ablation, or high-fat diet feeding increases islet size and β-cell mass in male mice. Here we determined if reducing ghrelin also enlarges...
6.
Gupta D, Burstein A, Schwalbe D, Shankar K, Varshney S, Singh O, et al.
J Clin Invest
. 2023 Dec;
133(24).
PMID: 38099492
Ghrelin exerts key effects on islet hormone secretion to regulate blood glucose levels. Here, we sought to determine whether ghrelin's effects on islets extend to the alteration of islet size...
7.
Singh O, Ogden S, Varshney S, Shankar K, Gupta D, Paul S, et al.
JCI Insight
. 2023 Nov;
8(24).
PMID: 37962950
Previous studies have implicated the orexigenic hormone ghrelin as a mediator of exercise endurance and the feeding response postexercise. Specifically, plasma ghrelin levels nearly double in mice when they are...
8.
Shankar K, Varshney S, Gupta D, Mani B, Osborne-Lawrence S, Metzger N, et al.
Front Endocrinol (Lausanne)
. 2023 Jun;
14:1181856.
PMID: 37334290
Introduction: Recurrent episodes of insulin-induced hypoglycemia in patients with diabetes mellitus can result in hypoglycemia-associated autonomic failure (HAAF), which is characterized by a compromised response to hypoglycemia by counterregulatory hormones...
9.
Osborne-Lawrence S, Lawrence C, Metzger N, Klavon J, Baig H, Richard C, et al.
Obesity (Silver Spring)
. 2023 May;
31(6):1644-1654.
PMID: 37161883
Objective: Prader-Willi syndrome (PWS) is a multisystem genetic disorder. Unfortunately, none of several mouse models carrying PWS mutations emulates the entirety of the human PWS phenotype, including hyperphagia plus obesity....
10.
Shankar K, Takemi S, Gupta D, Varshney S, Mani B, Osborne-Lawrence S, et al.
JCI Insight
. 2021 Sep;
6(18).
PMID: 34473648
Mechanisms underlying postprandial and obesity-associated plasma ghrelin reductions are incompletely understood. Here, using ghrelin cell-selective insulin receptor-KO (GhIRKO) mice, we tested the impact of insulin, acting via ghrelin cell-expressed insulin...