Bharath K Mani
Overview
Explore the profile of Bharath K Mani including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
36
Citations
757
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Varshney S, Shankar K, Kerr H, Anderson L, Gupta D, Metzger N, et al.
Endocrinology
. 2024 Sep;
165(11).
PMID: 39331742
The hormone ghrelin serves a protective role in cancer-related anorexia-cachexia syndrome (CACS)-a condition in which plasma levels of ghrelin rise, its administration lessens CACS severity, and experimentally reduced signaling by...
2.
Shankar K, Metzger N, Lawrence C, Gupta D, Osborne-Lawrence S, Varshney S, et al.
Mol Metab
. 2024 May;
84:101950.
PMID: 38697291
Objective: The number of individuals affected by metabolic dysfunction associated fatty liver disease [1] is on the rise, yet hormonal contributors to the condition remain incompletely described and only a...
3.
Shankar K, Varshney S, Gupta D, Mani B, Osborne-Lawrence S, Metzger N, et al.
Front Endocrinol (Lausanne)
. 2023 Jun;
14:1181856.
PMID: 37334290
Introduction: Recurrent episodes of insulin-induced hypoglycemia in patients with diabetes mellitus can result in hypoglycemia-associated autonomic failure (HAAF), which is characterized by a compromised response to hypoglycemia by counterregulatory hormones...
4.
Aguggia J, Cornejo M, Fernandez G, De Francesco P, Mani B, Cassano D, et al.
Psychoneuroendocrinology
. 2022 Mar;
139:105716.
PMID: 35290931
Ghrelin is a stomach-derived hormone that acts via the growth hormone secretagogue receptor (GHSR). Recent evidence suggests that some of ghrelin's actions may be mediated via the supramammillary nucleus (SuM)....
5.
Shankar K, Takemi S, Gupta D, Varshney S, Mani B, Osborne-Lawrence S, et al.
JCI Insight
. 2021 Sep;
6(18).
PMID: 34473648
Mechanisms underlying postprandial and obesity-associated plasma ghrelin reductions are incompletely understood. Here, using ghrelin cell-selective insulin receptor-KO (GhIRKO) mice, we tested the impact of insulin, acting via ghrelin cell-expressed insulin...
6.
Shankar K, Metzger N, Singh O, Mani B, Osborne-Lawrence S, Varshney S, et al.
Mol Metab
. 2021 Aug;
53:101327.
PMID: 34428557
Objective: The hormone liver-expressed antimicrobial peptide-2 (LEAP2) is a recently identified antagonist and an inverse agonist of the growth hormone secretagogue receptor (GHSR). GHSR's other well-known endogenous ligand, acyl-ghrelin, increases...
7.
Gupta D, Dowsett G, Mani B, Shankar K, Osborne-Lawrence S, Metzger N, et al.
Endocrinology
. 2021 Jul;
162(10).
PMID: 34289060
Islets represent an important site of direct action of the hormone ghrelin, with expression of the ghrelin receptor (growth hormone secretagogue receptor; GHSR) having been localized variably to alpha cells,...
8.
Deschaine S, Farokhnia M, Gregory-Flores A, Zallar L, You Z, Sun H, et al.
Addict Biol
. 2021 Apr;
27(1):e13033.
PMID: 33908131
Ghrelin is a gastric-derived peptide hormone with demonstrated impact on alcohol intake and craving, but the reverse side of this bidirectional link, that is, the effects of alcohol on the...
9.
Shankar K, Gupta D, Mani B, Findley B, Osborne-Lawrence S, Metzger N, et al.
Front Endocrinol (Lausanne)
. 2020 Oct;
11:606.
PMID: 33042003
Insulin-induced hypoglycemia is a major limiting factor in maintaining optimal blood glucose in patients with type 1 diabetes and advanced type 2 diabetes. Luckily, a counterregulatory response (1) system exists...
10.
Mani B, Osborne-Lawrence S, Metzger N, Zigman J
Am J Physiol Endocrinol Metab
. 2020 Jun;
319(2):E330-E337.
PMID: 32543942
Ghrelin is a predominantly stomach-derived peptide hormone with many actions including regulation of food intake, body weight, and blood glucose. Plasma ghrelin levels are robustly regulated by feeding status, with...