Shenshen Cai
Overview
Explore the profile of Shenshen Cai including associated specialties, affiliations and a list of published articles.
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17
Citations
1322
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Recent Articles
1.
Baranov P, Lin H, McCabe K, Gale D, Cai S, Lieppman B, et al.
J Ocul Pharmacol Ther
. 2017 Apr;
33(5):412-422.
PMID: 28441076
Purpose: Degenerative diseases of the retina, such as retinitis pigmentosa and age-related macular degeneration, are characterized by the irreversible loss of photoreceptors. Several growth factors, including glial cell derived neurotrophic...
2.
Discher D, Ortiz V, Srinivas G, Klein M, Kim Y, Christian D, et al.
Prog Polym Sci
. 2014 Apr;
32(8-9):838-857.
PMID: 24692840
Polymersomes are self-assembled shells of amphiphilic block copolymers that are currently being developed by many groups for fundamental insights into the nature of self-assembled states as well as for a...
3.
Rehfeldt F, Brown A, Raab M, Cai S, Zajac A, Zemel A, et al.
Integr Biol (Camb)
. 2012 Feb;
4(4):422-30.
PMID: 22344328
Physical features of microenvironments such as matrix elasticity E can clearly influence cell morphology and cell phenotype, but many differences between model matrices raise questions as to whether a standard...
4.
Shuvaev V, Ilies M, Simone E, Zaitsev S, Kim Y, Cai S, et al.
ACS Nano
. 2011 Aug;
5(9):6991-9.
PMID: 21838300
The endothelial lining of the lumen of blood vessels is a key therapeutic target for many human diseases. Polymeric filomicelles that self-assemble from polyethylene oxide (PEO)-based diblock copolymers are long...
5.
Christian D, Cai S, Garbuzenko O, Harada T, Zajac A, Minko T, et al.
Mol Pharm
. 2009 Mar;
6(5):1343-52.
PMID: 19249859
Shape effects of synthetic carriers are largely unexplored in vivo, although recent findings suggest that flexible filaments can persist in the circulation even if microns in length. Here, to better...
6.
Kim Y, Tewari M, Pajerowski J, Cai S, Sen S, Williams J, et al.
J Control Release
. 2008 Dec;
134(2):132-40.
PMID: 19084037
siRNA and antisense oligonucleotides, AON, have similar size and negative charge and are often packaged for in vitro delivery with cationic lipids or polymers-but exposed positive charge is problematic in...
7.
Christian D, Cai S, Bowen D, Kim Y, Pajerowski J, Discher D
Eur J Pharm Biopharm
. 2008 Nov;
71(3):463-74.
PMID: 18977437
Polymersomes are polymer-based vesicular shells that form upon hydration of amphiphilic block copolymers. These high molecular weight amphiphiles impart physicochemical properties that allow polymersomes to stably encapsulate or integrate a...
8.
Peattie R, Pike D, Yu B, Cai S, Shu X, Prestwich G, et al.
Drug Deliv
. 2008 Aug;
15(6):389-97.
PMID: 18686083
The hypothesis that incorporation of small amounts (0.3% w/w) of modified heparin in thiol-modified hyaluronan or HA and gelatin hydrogels would regulate release of cytokine growth factors (GFs) from those...
9.
Geng Y, Dalhaimer P, Cai S, Tsai R, Tewari M, Minko T, et al.
Nat Nanotechnol
. 2008 Jul;
2(4):249-55.
PMID: 18654271
Interaction of spherical particles with cells and within animals has been studied extensively, but the effects of shape have received little attention. Here we use highly stable, polymer micelle assemblies...
10.
Cai S, Vijayan K, Cheng D, Lima E, Discher D
Pharm Res
. 2007 Jun;
24(11):2099-109.
PMID: 17564817
Purpose: Worm-like and spherical micelles are both prepared here from the same amphiphilic diblock copolymer, poly(ethylene oxide)-b-poly (epsilon-caprolactone) (PEO [5 kDa]-PCL [6.5 kDa]) in order to compare loading and delivery...