Tamara Minko
Overview
Explore the profile of Tamara Minko including associated specialties, affiliations and a list of published articles.
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109
Citations
4037
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Recent Articles
1.
Lee D, Shen A, Shah M, Garbuzenko O, Minko T
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408684
Our study took an innovative approach by evaluating, in vivo, the efficacy of intranasal (IN) administration of liposomal formulations of donepezil, memantine, and beta-site amyloid precursor protein-cleaving enzyme (BACE-1) siRNA,...
2.
Lee D, Shen A, Garbuzenko O, Minko T
AAPS J
. 2024 Sep;
26(5):99.
PMID: 39231845
β-site amyloid precursor protein cleaving enzyme (BACE1) represents a key target for Alzheimer's disease (AD) therapy because it is essential for producing the toxic amyloid β (Aβ) peptide that plays...
3.
Romaniuk-Drapala A, Skupin-Mrugalska P, Garbuzenko O, Hatefi A, Minko T
Cancer Cell Int
. 2024 Aug;
24(1):285.
PMID: 39135053
Background: Olaparib is a PARP inhibitor inducing synthetic lethality in tumors with deficient homologous recombination (HRD) caused by BRCA1/2 mutations. The FDA has approved monotherapy for first-line platinum-sensitive, recurrent high-grade...
4.
5.
Gu X, Majumder J, Taratula O, Kuzmov A, Garbuzenko O, Pogrebnyak N, et al.
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791582
A novel nanotechnology-based drug delivery system (DDS) targeted at pancreatic cancer cells was developed, characterized, and tested. The system consisted of liposomes as carriers, an anticancer drug (paclitaxel) as a...
6.
Gu X, Minko T
Cancers (Basel)
. 2024 Apr;
16(8).
PMID: 38672671
Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest cancers, presents significant challenges in diagnosis and treatment due to its aggressive, metastatic nature and lack of early detection methods. A key...
7.
Garbuzenko O, Sapiezynski J, Girda E, Rodriguez-Rodriguez L, Minko T
Small
. 2024 Feb;
20(41):e2307462.
PMID: 38342698
The response to treatment is substantially varied between individual patients with ovarian cancer. However, chemotherapy treatment plans rarely pay sufficient attention to the mentioned factors. Instead, standardized treatment protocols are...
8.
Shen A, Malekshah O, Pogrebnyak N, Minko T
J Control Release
. 2023 May;
359:1-11.
PMID: 37225092
Data show a decrease in the risk of hospitalization and death from COVID-19. To date, global vaccinations for SARS-CoV-2 protections are underway, but additional treatments are urgently needed to prevent...
9.
Pozharov V, Minko T
Pharmaceutics
. 2023 Jan;
15(1).
PMID: 36678823
Over the past decades, many drugs based on the use of nanotechnology and nucleic acids have been developed. However, until recently, most of them remained at the stage of pre-clinical...
10.
Gildiz S, Minko T
Pharm Res
. 2022 Nov;
40(1):123-144.
PMID: 36376606
Anticancer vaccines represent a promising approach for effective treatment of cancer and along with recent advantages of nucleic acid-based vaccines for other diseases form a prospective and potentially efficacious direction...