Scott P Heximer
Overview
Explore the profile of Scott P Heximer including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
1225
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0
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Recent Articles
1.
Yazaki K, Dewar M, Dauz J, Akazawa Y, Hui L, Sun M, et al.
Am J Physiol Heart Circ Physiol
. 2024 Oct;
328(1):H58-H74.
PMID: 39422363
Right ventricular (RV) function determines outcomes in RV pressure loading. A better understanding of the time-course and regional distribution of RV remodeling may help optimize targets and timing for therapeutic...
2.
Zhou Y, Bonafiglia Q, Zhang H, Heximer S, Bendeck M
Am J Physiol Heart Circ Physiol
. 2023 Jan;
324(4):H391-H410.
PMID: 36607797
This study reports a new methodology for right heart imaging by ultrasound in mice under right ventricular (RV) pressure overload. Pulmonary artery constriction (PAC) or sham surgeries were performed on...
3.
Kroetsch J, Lidington D, Alibhai F, Reitz C, Zhang H, Dinh D, et al.
Cardiovasc Res
. 2022 Nov;
119(6):1403-1415.
PMID: 36418171
Aims: Circadian rhythms orchestrate important functions in the cardiovascular system: the contribution of microvascular rhythms to cardiovascular disease progression/severity is unknown. This study hypothesized that (i) myogenic reactivity in skeletal...
4.
Mohabeer A, Kroetsch J, McFadden M, Khosraviani N, Broekelmann T, Hou G, et al.
Matrix Biol Plus
. 2021 Oct;
12:100085.
PMID: 34693248
Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in...
5.
Bastin G, Luu L, Batchuluun B, Mighiu A, Beadman S, Zhang H, et al.
Biomedicines
. 2021 Aug;
9(8).
PMID: 34440212
A number of diverse G-protein signaling pathways have been shown to regulate insulin secretion from pancreatic β-cells. Accordingly, regulator of G-protein signaling (RGS) proteins have also been implicated in coordinating...
6.
Shah H, Hacker A, Langburt D, Dewar M, McFadden M, Zhang H, et al.
J Proteome Res
. 2021 Apr;
20(5):2867-2881.
PMID: 33789425
Heart failure (HF) is associated with pathological remodeling of the myocardium, including the initiation of fibrosis and scar formation by activated cardiac fibroblasts (CFs). Although early CF-dependent scar formation helps...
7.
Guo J, Pereira T, Mori Y, Gonzalez Medina M, Breen D, Dalvi P, et al.
J Vasc Res
. 2020 Aug;
57(6):325-340.
PMID: 32777783
We have shown that both insulin and resveratrol (RSV) decrease neointimal hyperplasia in chow-fed rodents via mechanisms that are in part overlapping and involve the activation of endothelial nitric oxide...
8.
Bastin G, Dissanayake K, Langburt D, Tam A, Lee S, Lachhar K, et al.
J Cell Sci
. 2020 Jun;
133(12).
PMID: 32501280
Intracellular pools of the heterotrimeric G-protein α-subunit Gαi3 (encoded by ) have been shown to promote growth factor signaling, while at the same time inhibiting the activation of JNK and...
9.
Dinh D, Lidington D, Kroetsch J, Ng C, Zhang H, Nedospasov S, et al.
Front Physiol
. 2020 Jun;
11:402.
PMID: 32477159
Subarachnoid hemorrhage (SAH) is a devastating cerebral event caused by an aneurysmal rupture. In addition to neurological injury, SAH has significant effects on cardiac function and the peripheral microcirculation. Since...
10.
Lidington D, Fares J, Uhl F, Dinh D, Kroetsch J, Sauve M, et al.
JACC Basic Transl Sci
. 2020 Jan;
4(8):940-958.
PMID: 31909302
Heart failure (HF) and subarachnoid hemorrhage (SAH) chronically reduce cerebral perfusion, which negatively affects clinical outcome. This work demonstrates a strong relationship between cerebral artery cystic fibrosis transmembrane conductance regulator...