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Satish C Kalhan

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Articles 74
Citations 3324
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Recent Articles
1.
Rojas-Rodriguez R, Price L, Somogie J, Hauguel-De Mouzon S, Kalhan S, Catalano P
J Clin Endocrinol Metab . 2022 Jun; 107(9):e3759-e3768. PMID: 35686573
Context: Pregnancy is characterized by progressive decreases in glucose insulin sensitivity. Low insulin sensitivity resulting in hyperglycemia is associated with higher neonatal adiposity. However, less is known regarding lipid metabolism,...
2.
Heresi G, Mey J, Bartholomew J, Haddadin I, Tonelli A, Dweik R, et al.
Pulm Circ . 2020 Feb; 10(1):2045894019890553. PMID: 32110382
We aimed to characterize the plasma metabolome of chronic thromboembolic pulmonary hypertension patients using a high-throughput unbiased omics approach. We collected fasting plasma from a peripheral vein in 33 operable...
3.
Bhat D, Gruca L, Bennett C, Katre P, Kurpad A, Yajnik C, et al.
PLoS One . 2018 May; 13(5):e0196970. PMID: 29795596
Background: Methionine loading test (MLT) has been used primarily to identify defects in transsulfuration of homocysteine in cystathionine beta synthase deficiency. It may not be as useful to evaluate remethylation...
4.
Kalhan S
J Pediatr Gastroenterol Nutr . 2018 May; 66 Suppl 3:S42-S45. PMID: 29762376
Starch, a major source of carbohydrates in human nutrition, is extensively hydrolyzed in the gastrointestinal tract of children and adults. A small fraction of the ingested starch reaches the cecum...
5.
Calkins K, Thamotharan S, Dai Y, Shin B, Kalhan S, Devaskar S
Nutr Res . 2018 Apr; 54:93-104. PMID: 29685622
Intrauterine growth restriction is linked to decreased lean body mass and insulin resistance. The mammalian target of rapamycin (mTOR) regulates muscle mass and glucose metabolism; however, little is known about...
6.
Xu W, Comhair S, Janocha A, Lara A, Mavrakis L, Bennett C, et al.
PLoS One . 2017 Aug; 12(8):e0183066. PMID: 28797075
Aims: Arginine metabolism via inducible nitric oxide synthase (iNOS) and arginase 2 (ARG2) is higher in asthmatics than in healthy individuals. We hypothesized that a sub-phenotype of asthma might be...
7.
Hendrikx T, Watzenbock M, Walenbergh S, Amir S, Gruber S, Ozsvar Kozma M, et al.
BMC Med . 2016 Jul; 14(1):107. PMID: 27443391
Background: Lipid oxidation of membrane phospholipids is accompanied by the formation of oxidation-specific epitopes (OSE). These epitopes are recognized by specific antibodies and represent danger-associated molecular patterns that are generated...
8.
Kalhan S
Mol Cell Endocrinol . 2016 Jun; 435:48-60. PMID: 27267668
One carbon metabolism or methyl transfer, a crucial component of metabolism in all cells and tissues, supports the critical function of synthesis of purines, thymidylate and methylation via multiple methyl...
9.
Xu W, Ghosh S, Comhair S, Asosingh K, Janocha A, Mavrakis D, et al.
J Clin Invest . 2016 May; 126(7):2465-81. PMID: 27214549
High levels of arginine metabolizing enzymes, including inducible nitric oxide synthase (iNOS) and arginase (ARG), are typical in asthmatic airway epithelium; however, little is known about the metabolic effects of...
10.
Kalhan S, Gruca L, Marczewski S, Bennett C, Kummitha C
Amino Acids . 2015 Oct; 48(3):677-687. PMID: 26480831
Creatine kinetics were measured in young healthy subjects, eight males and seven females, age 20-30 years, after an overnight fast on creatine-free diet. Whole body turnover of glycine and its...