Sarah J Mitchell
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Explore the profile of Sarah J Mitchell including associated specialties, affiliations and a list of published articles.
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90
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3744
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Recent Articles
11.
Thomas C, Erni R, Wu J, Fischer F, Lamers G, Grigolon G, et al.
Nat Commun
. 2023 Dec;
14(1):8142.
PMID: 38065964
To ameliorate or even prevent signatures of aging in ultimately humans, we here report the identification of a previously undescribed polyacetylene contained in the root of carrots (Daucus carota), hereafter...
12.
Kip P, Sluiter T, MacArthur M, Tao M, Jung J, Mitchell S, et al.
bioRxiv
. 2023 Nov;
PMID: 37961405
Short-term preoperative methionine restriction (MetR) shows promise as a translatable strategy to modulate the body's response to surgical injury. Its application, however, to improve post-interventional vascular remodeling remains underexplored. Here,...
13.
Mitchell S, MacArthur M, Kane A
Br J Clin Pharmacol
. 2023 Sep;
91(1):5-7.
PMID: 37675638
Preclinical models have been the backbone of translational research for more than a century. Rats and mice are critical models in the preliminary stages of drug testing, both for determining...
14.
Knufinke M, MacArthur M, Ewald C, Mitchell S
Front Aging
. 2023 Jun;
4:1172789.
PMID: 37305228
With an increasing aging population, the burden of age-related diseases magnifies. To alleviate this burden, geroprotection has been an area of intense research focus with the development of pharmacological interventions...
15.
Kiesworo K, MacArthur M, Kip P, Agius T, Macabrey D, Lambelet M, et al.
JVS Vasc Sci
. 2023 Feb;
4:100095.
PMID: 36852171
Objective: Hydrogen sulfide is a proangiogenic gas produced primarily by the transsulfuration enzyme cystathionine-γ-lyase (CGL). CGL-dependent hydrogen sulfide production is required for neovascularization in models of peripheral arterial disease. However,...
16.
Winicki N, Nanavati A, Morrell C, Moen J, Axsom J, Krawczyk M, et al.
Front Cardiovasc Med
. 2023 Feb;
9:1096887.
PMID: 36741836
Background: Aging is associated with increased levels of reactive oxygen species and inflammation that disrupt proteostasis and mitochondrial function and leads to organism-wide frailty later in life. ARA290 (cibinetide), an...
17.
MacArthur M, Mitchell S
Lab Anim (NY)
. 2023 Jan;
52(3):61-62.
PMID: 36693909
No abstract available.
18.
Yang J, Hayano M, Griffin P, Amorim J, Bonkowski M, Apostolides J, et al.
Cell
. 2023 Jan;
186(2):305-326.e27.
PMID: 36638792
All living things experience an increase in entropy, manifested as a loss of genetic and epigenetic information. In yeast, epigenetic information is lost over time due to the relocalization of...
19.
Grundler F, Viallon M, Mesnage R, Ruscica M, von Schacky C, Madeo F, et al.
Front Nutr
. 2022 Dec;
9:951000.
PMID: 36466423
Clinical Trial Registration: [ClinicalTrials.gov], identifier [NCT05031598].
20.
Turner N, Wahid A, Oliver P, Gardiner C, Chapman H, Khan Ppi Co-Author D, et al.
Palliat Med
. 2022 Dec;
37(2):235-243.
PMID: 36461707
Background: The need for end-of-life care in the community increased significantly during the COVID-19 pandemic. Primary care services, including general practitioners and community nurses, had a critical role in providing...