Sara Marsango
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Explore the profile of Sara Marsango including associated specialties, affiliations and a list of published articles.
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26
Citations
251
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Recent Articles
11.
Jenkins L, Marsango S, Mancini S, Al Mahmud Z, Morrison A, McElroy S, et al.
ACS Pharmacol Transl Sci
. 2021 Oct;
4(5):1598-1613.
PMID: 34661077
GPR84 is a poorly characterized, nominally orphan, proinflammatory G protein-coupled receptor that can be activated by medium chain length fatty acids. It is attracting considerable interest as a potential therapeutic...
12.
Ward R, Pediani J, Marsango S, Jolly R, Stoneman M, Biener G, et al.
J Biol Chem
. 2020 Dec;
296:100139.
PMID: 33268380
CXCR4, a member of the family of chemokine-activated G protein-coupled receptors, is widely expressed in immune response cells. It is involved in both cancer development and progression as well as...
13.
Marsango S, Barki N, Jenkins L, Tobin A, Milligan G
Br J Pharmacol
. 2020 Sep;
179(14):3529-3541.
PMID: 32869860
Despite the importance of members of the GPCR superfamily as targets of a broad range of effective medicines many GPCRs remain poorly characterised. GPR84 is an example. Expression of GPR84...
14.
Milligan G, Ward R, Marsango S
Curr Opin Cell Biol
. 2018 Nov;
57:40-47.
PMID: 30453145
G protein-coupled receptors (GPCRs) are an extensive class of trans-plasma membrane proteins that function to regulate a wide range of physiological functions. Despite a general perception that GPCRs exist as...
15.
Marsango S, Ward R, Alvarez-Curto E, Milligan G
Neuropharmacology
. 2017 Nov;
136(Pt C):401-410.
PMID: 29146505
G protein-coupled receptors (GPCRs) have been classically described as monomeric entities that function by binding in a 1:1 stoichiometric ratio to both ligand and downstream signalling proteins. However, in recent...
16.
Pediani J, Ward R, Marsango S, Milligan G
Trends Pharmacol Sci
. 2017 Oct;
39(2):175-186.
PMID: 29032835
Spatial intensity distribution analysis (SpIDA) is a recently developed approach for determining quaternary structure information on fluorophore-labelled proteins of interest in situ. It can be applied to live or fixed...
17.
Marsango S, Caltabiano G, Jimenez-Roses M, Millan M, Pediani J, Ward R, et al.
Sci Rep
. 2017 May;
7(1):2134.
PMID: 28522847
The dopamine D receptor (DR) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that...
18.
Milligan G, Liste M, Caltabiano G, Alvarez-Curto E, Marsango S
Springerplus
. 2016 Jul;
4(Suppl 1):L7.
PMID: 27386224
No abstract available.
19.
Pediani J, Ward R, Godin A, Marsango S, Milligan G
J Biol Chem
. 2016 Apr;
291(25):13132-46.
PMID: 27080256
Although rhodopsin-like G protein-coupled receptors can exist as both monomers and non-covalently associated dimers/oligomers, the steady-state proportion of each form and whether this is regulated by receptor ligands are unknown....
20.
Marsango S, Varela M, Milligan G
Methods Mol Biol
. 2015 Aug;
1335:95-105.
PMID: 26260596
Fluorescence resonance energy transfer (FRET) is an approach widely used to detect protein-protein interactions in live cells. This approach is based on the sensitization of an "acceptor" molecule by the...