Roberta Menafra
Overview
Explore the profile of Roberta Menafra including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
850
Followers
0
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Related Specialties
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Recent Articles
1.
Voskamp A, Tak T, Gerdes M, Menafra R, Duijster E, Jochems S, et al.
J Exp Med
. 2023 Aug;
220(9).
PMID: 37594459
No abstract available.
2.
van Bergen C, Kloet S, Quinten E, Sepulveda Yanez J, Menafra R, Griffioen M, et al.
Blood Adv
. 2023 Jul;
7(19):5812-5816.
PMID: 37493974
No abstract available.
3.
Voskamp A, Tak T, Gerdes M, Menafra R, Duijster E, Jochems S, et al.
J Exp Med
. 2023 Jul;
220(9).
PMID: 37428185
Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. We investigated their role at nasal mucosa following allergen challenge with house dust mite. We combined single-cell proteome and transcriptome...
4.
Kaiser F, Janowska I, Menafra R, de Gier M, Korzhenevich J, Pico-Knijnenburg I, et al.
Blood
. 2023 Jun;
142(13):1113-1130.
PMID: 37369082
Although absence of interleukin-7 (IL-7) signaling completely abrogates T and B lymphopoiesis in mice, patients with severe combined immunodeficiency caused by mutations in the IL-7 receptor α chain (IL-7Rα) still...
5.
Graansma L, Zhai Q, Busscher L, Menafra R, van den Berg R, Kloet S, et al.
Front Pharmacol
. 2023 Mar;
14:1076574.
PMID: 36937863
Inter-individual differences in drug response based on genetic variations can lead to drug toxicity and treatment inefficacy. A large part of this variability is caused by genetic variants in pharmacogenes....
6.
van der Lee M, Rowell W, Menafra R, Guchelaar H, Swen J, Anvar S
Pharmacogenomics J
. 2021 Nov;
22(1):75-81.
PMID: 34741133
The use of pharmacogenomics in clinical practice is becoming standard of care. However, due to the complex genetic makeup of pharmacogenes, not all genetic variation is currently accounted for. Here,...
7.
Hutchinson S, Foulon S, Crouzols A, Menafra R, Rotureau B, Griffiths A, et al.
PLoS Pathog
. 2021 Sep;
17(9):e1009904.
PMID: 34543350
The long and complex Trypanosoma brucei development in the tsetse fly vector culminates when parasites gain mammalian infectivity in the salivary glands. A key step in this process is the...
8.
van der Lee M, Allard W, Vossen R, Baak-Pablo R, Menafra R, Deiman B, et al.
Sci Transl Med
. 2021 Jul;
13(603).
PMID: 34290055
Pharmacogenomics is a key component of personalized medicine that promises safer and more effective drug treatment by individualizing drug choice and dose based on genetic profiles. In clinical practice, genetic...
9.
Grow E, Weaver B, Smith C, Guo J, Stein P, Shadle S, et al.
Nat Genet
. 2021 Jul;
53(8):1207-1220.
PMID: 34267371
In mammalian embryos, proper zygotic genome activation (ZGA) underlies totipotent development. Double homeobox (DUX)-family factors participate in ZGA, and mouse Dux is required for forming cultured two-cell (2C)-like cells. Remarkably,...
10.
Darvish Shafighi S, Kielbasa S, Sepulveda-Yanez J, Monajemi R, Cats D, Mei H, et al.
Genome Med
. 2021 Mar;
13(1):45.
PMID: 33761980
Background: Drawing genotype-to-phenotype maps in tumors is of paramount importance for understanding tumor heterogeneity. Assignment of single cells to their tumor clones of origin can be approached by matching the...