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Szymon M Kielbasa

Explore the profile of Szymon M Kielbasa including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 2828
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Recent Articles
1.
Oksza-Orzechowski K, Quinten E, Shafighi S, Kielbasa S, van Kessel H, de Groen R, et al.
Genome Biol . 2024 Nov; 25(1):286. PMID: 39501370
Tumours exhibit high genotypic and transcriptional heterogeneity. Both affect cancer progression and treatment, but have been predominantly studied separately in follicular lymphoma. To comprehensively investigate the evolution and genotype-to-phenotype maps...
2.
Voskamp A, Tak T, Gerdes M, Menafra R, Duijster E, Jochems S, et al.
J Exp Med . 2023 Aug; 220(9). PMID: 37594459
No abstract available.
3.
van Bergen C, Kloet S, Quinten E, Sepulveda Yanez J, Menafra R, Griffioen M, et al.
Blood Adv . 2023 Jul; 7(19):5812-5816. PMID: 37493974
No abstract available.
4.
Voskamp A, Tak T, Gerdes M, Menafra R, Duijster E, Jochems S, et al.
J Exp Med . 2023 Jul; 220(9). PMID: 37428185
Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. We investigated their role at nasal mucosa following allergen challenge with house dust mite. We combined single-cell proteome and transcriptome...
5.
Dang H, Harryvan T, Liao C, Danen E, Spalburg V, Kielbasa S, et al.
Cell Mol Gastroenterol Hepatol . 2023 Apr; 16(1):107-131. PMID: 37085135
Background & Aims: Improving clinical management of early stage colorectal cancers (T1CRCs) requires a better understanding of their underlying biology. Accumulating evidence shows that cancer-associated fibroblasts (CAFs) are important determinants...
6.
Kleiburg F, Heijmen L, Gelderblom H, Kielbasa S, Bovee J, de Geus-Oei L
Br J Radiol . 2023 Feb; 96(1145):20220886. PMID: 36728839
Bone and soft tissue sarcomas are a group of rare malignant tumours with major histological and anatomical varieties. In a metastatic setting, sarcomas have a poor prognosis due to limited...
7.
Cordes M, Cante-Barrett K, van den Akker E, Moretti F, Kielbasa S, Vloemans S, et al.
Sci Immunol . 2022 Nov; 7(77):eade0182. PMID: 36367948
T cell development in the mouse thymus has been studied extensively, but less is known regarding T cell development in the human thymus. We used a combination of single-cell techniques...
8.
Heijkants R, Teunisse A, de Jong D, Glinkina K, Mei H, Kielbasa S, et al.
Cancers (Basel) . 2022 Sep; 14(18). PMID: 36139642
The tumor suppressor protein p53 has an important role in cell-fate determination. In cancer cells, the activity of p53 is frequently repressed by high levels of MDMX and/or MDM2. MDM2...
9.
Anijs R, Laghmani E, Unlu B, Kielbasa S, Mei H, Cannegieter S, et al.
Res Pract Thromb Haemost . 2022 Jul; 6(5):e12749. PMID: 35794963
Background: Colorectal cancer patients have an increased risk of developing venous thromboembolism (VTE), resulting in increased morbidity and mortality. Because the exact mechanism is yet unknown, risk prediction is still...
10.
Ge Y, van Roon L, Chen H, Methorst R, Paton M, DeRuiter M, et al.
J Vis Exp . 2022 Apr; (181). PMID: 35404341
The cardiac autonomic nervous system is crucial in controlling cardiac function, such as heart rate and cardiac contractility, and is divided into sympathetic and parasympathetic branches. Normally, there is a...